Who Should I Start? Tyjae Spears or Isaac Guerendo

Sunday, August 10, 1:05 PM

Tennessee Titans head coach Brian Callahan said that running back Tyjae Spears (ankle) will miss a couple of weeks at least after he suffered a high-ankle sprain in Saturday's preseason opener against the Tampa Bay Buccaneers and had to be carted off the field. This means that Spears should be considered questionable to play in the Week 1 regular-season opener on Sept. 7 against the Denver Broncos. The 24-year-old was set to take on a bigger role in the Titans' backfield to take some of the burden off of Tony Pollard, but that might have to wait for now. With Spears out of action for at least a couple of weeks, it will create more change-of-pace opportunities for both Julius Chestnut and rookie Kalel Mullings behind Pollard. With the injury, Spears is now ranked as the RB46 in fantasy at RotoBaller.

Monday, August 4, 3:26 PM

San Francisco 49ers running back Isaac Guerendo (shoulder) is expected to miss a couple of weeks, according to Matt Maiocco of NBC Sports. Guerendo will miss time after getting injured during Saturday's training camp practice. While the 25-year-old still has time to get ready for the start of the regular season, he will miss important reps during practice and the preseason as he gets ready to serve as Christian McCaffrey's primary backup in 2025. With Guerendo now out for a few weeks, it will give rookie Jordan James more opportunities to run with the first-team offense when CMC needs a breather. In addition to James, Patrick Taylor Jr. and Ameer Abdullah should see more work in practices. When healthy, Guerendo's raw athletic abilities make him an intriguing handcuff if you take the leap on McCaffrey.