Who Should I Start? Tyjae Spears or Isaac Guerendo

Tuesday, September 16, 9:39 PM

Tennessee Titans running back Tyjae Spears (ankle) suffered a high ankle sprain in preseason action and was placed on Injured Reserve before the start of the regular season. Given the nature of Spears' injury, he may be able to return as soon as he is eligible in Week 5 against the Arizona Cardinals. The Titans have been a one-man show at running back so far this season, with Tony Pollard having logged 38 of the team's 40 rush attempts by running backs through the team's first two games. However, this was not the case down the stretch of 2024, when Spears logged double-digit touches in each of the final three games he played. Spears finished the 2024 season with 536 yards from scrimmage and five touchdowns across 12 games and should have a consistent role in the Titans' offense once healthy in 2025. In fantasy leagues where he is available, Spears is a worthy stash in an IR spot ahead of his impending return.

Wednesday, September 17, 12:37 PM

San Francisco 49ers running back Isaac Guerendo entered the 2025 season as a prime handcuff for fantasy managers who were looking to score Christian McCaffrey at a discount early in drafts. However, Guerendo's fantasy value took a massive hit when the Niners acquired Brian Robinson Jr. from the Washington Commanders. B-Rob has been McCaffrey's backup through two weeks, relegating Guerendo to a distant RB3 role. In the Week 2 win over the New Orleans Saints, the 25-year-old didn't play a single snap on offense, with all 17 of his snaps coming on special teams. Guerendo averaged a healthy 5.0 yards per carry on 84 rushing attempts for 420 yards and four touchdowns in 16 games (three starts) as a rookie in 2024 when CMC was bothered by injuries, but currently, he's well off the fantasy radar in single-year leagues going into Week 3 against the division-rival Arizona Cardinals.