Who Should I Start? Tyjae Spears or Isaac Guerendo

Saturday, December 13, 10:54 AM

Tennessee Titans running back Tyjae Spears remains firmly on the fantasy radar as an RB3/flex option in full-PPR leagues ahead of Sunday's Week 15 contest against the San Francisco 49ers. Spears lost key volume to Tony Pollard (25 carries, 161 yards, two touchdowns) last week, but he still maintained a sizable role on passing downs. He has at least three targets in all eight of his games this season, and he's averaging an impressive 4.3 catches per game over the last four weeks. Spears' impressive pass-catching volume has allowed him to rank as the overall RB34 in fantasy points per game since Week 6 (minimum four games played). This week, he takes on a 49ers defense that has struggled against pass-catching backs. Specifically, the Niners have allowed the most catches, eighth-most receiving yards, and eighth-most receiving touchdowns to opposing running backs in 2025. While Pollard has generated most of the buzz after last week's big game, Spears should be the name to get excited about in this backfield, given how often pass-catching backs excel against this 49ers run defense. Spears should be viewed as a strong RB3/flex option in Week 15.

Tuesday, October 21, 9:16 PM

San Francisco 49ers running back Isaac Guerendo was thrust into action in his rookie season in the NFL in 2024 because Christian McCaffrey missed most of the year due to injuries. Guerendo finished with 84 rushing attempts for 420 yards and four touchdowns in 16 games (three starts) and also chipped in 15 catches on 16 targets as a pass-catcher for 152 yards. Fantasy managers probably viewed him as a pretty valuable handcuff for the injury-prone CMC going into 2025 drafts, but the Niners' acquisition of Brian Robinson Jr. before the season pretty much killed whatever fantasy appeal he had. Through the first seven weeks of his sophomore campaign, the 25-year-old former fourth-rounder has yet to play an offensive snap with CMC and B-Rob both staying healthy. Instead, Guerendo has been limited to a special teams role, returning five kickoffs for a combined 100 yards.