These are the top fantasy football players of the Buffalo Bills as ranked by Average Draft Position (ADP) in PPR-format mock drafts.
Data as of September 10, 2025.
| # | Name | Pos | Team | ADP | Bye |
|---|---|---|---|---|---|
| 1 | Josh Allen | QB | BUF | 2.12 | 7 |
| 2 | James Cook | RB | BUF | 3.11 | 7 |
| 3 | Khalil Shakir | WR | BUF | 8.01 | 7 |
| 4 | Keon Coleman | WR | BUF | 9.04 | 7 |
| 5 | Buffalo Defense | DEF | BUF | 11.11 | 7 |
| 6 | Dalton Kincaid | TE | BUF | 12.08 | 7 |
Josh Allen's current ADP is 2.12, which is the 12th pick of the 2nd round, and 23rd selection overall.
James Cook's current ADP is 3.11, which is the 11th pick of the 3rd round, and 34th selection overall.
Khalil Shakir's current ADP is 8.01, which is the 1st pick of the 8th round, and 84th selection overall.
Keon Coleman's current ADP is 9.04, which is the 4th pick of the 9th round, and 99th selection overall.
Buffalo Defense's current ADP is 11.11, which is the 11th pick of the 11th round, and 130th selection overall.
Dalton Kincaid's current ADP is 12.08, which is the 8th pick of the 12th round, and 139th selection overall.
| Week | Home/Away | Opponent |
|---|---|---|
| 1 | Home | Baltimore Ravens |
| 2 | Away | New York Jets |
| 3 | Home | Miami Dolphins |
| 4 | Home | New Orleans Saints |
| 5 | Home | New England Patriots |
| 6 | Away | Atlanta Falcons |
| 8 | Away | Carolina Panthers |
| 9 | Home | Kansas City Chiefs |
| 10 | Away | Miami Dolphins |
| 11 | Home | Tampa Bay Buccaneers |
| 12 | Away | Houston Texans |
| 13 | Away | Pittsburgh Steelers |
| 14 | Home | Cincinnati Bengals |
| 15 | Away | New England Patriots |
| 16 | Away | Cleveland Browns |
| 17 | Home | Philadelphia Eagles |
| 18 | Home | New York Jets |
Buffalo Bills running back James Cook had 16 carries, 117 rushing yards, and two rushing touchdowns during Sunday's Week 16 win over the Cleveland Browns. He also converted two targets into one catch for 17 receiving yards. Cook's quest for the NFL rushing title continued against a Browns defense that has been absolutely ripped apart by opposing running backs over the last three weeks. Buffalo's primary ball-carrier now has 14 touchdowns and over 1,800 scrimmage yards on the year, including five trips to the end zone in his last two games. Preseason concerns that Cook was due for regression have been completely unfounded, as he remains one of the top fantasy running backs while continuing to play a massive role around the goal line. He's a very strong RB1 option with a high ceiling heading into Week 17 against the Philadelphia Eagles.
December 21, 2025 5:54 PM EST
Buffalo Bills wide receiver Mecole Hardman (calf) is officially active for Sunday's game against the Cleveland Browns. Hardman was activated off Injured Reserve on Saturday and will play in place of Keon Coleman, who will serve as a healthy inactive for the third time this season. Hardman was upgraded to a full participant in practice on Thursday and Friday after being limited on Wednesday. The former Kansas City Chiefs wideout landed on IR after injuring his calf in his first game with the Bills in Week 11's win over the Tampa Bay Buccaneers. Hardman is unlikely to play a major role in the Bills' spread-out passing attack and shouldn't be in any fantasy lineups in Week 16.
December 21, 2025 12:14 PM EST
Buffalo Bills wide receiver Keon Coleman will be a healthy scratch for Sunday's game against the Cleveland Browns, NFL Network's Cameron Wolfe reports. The Bills recently activated Mecole Hardman (calf) off Injured Reserve, and he will be active in Coleman's place. Coleman was a healthy scratch in Weeks 11 and 12 for disciplinary reasons, and his Week 16 absence is reportedly a coach's decision. It's been a disappointing season for the second-year wideout, totalling 36 catches (55 targets) for 355 yards and four touchdowns in 12 games, with 112 of those yards coming in Week 1. With Coleman out again, Joshua Palmer, Brandin Cooks, Tyrell Shavers, and Hardman will all be in the mix for more opportunities behind Khalil Shakir, who remains Buffalo's clear WR1 on Sunday.
December 21, 2025 11:45 AM EST
The Buffalo Bills have elevated kicker Michael Badgley from the practice squad to the active roster and activated wide receiver Mecole Hardman (calf) from Injured Reserve. Badgley will be filling in for an injured Matt Prater (quadriceps), who could be looking at a multi-game absence. The 30-year-old Badgley was signed to the Bills' practice squad after beginning the season with the Indianapolis Colts, where he made 10 of his 11 field goal attempts and 18 of his 21 extra points in seven games. Hardman, on the other hand, landed on IR after injuring his calf in his first game with the Bills in Week 11's win over the Buccaneers. The 27-year-old wideout is unlikely to be a significant factor in the Bills' offense, but should play a role on special teams in Week 16's game versus the Cleveland Browns.
December 20, 2025 4:31 PM EST
Buffalo Bills tight end Dawson Knox caught three of four targets for 37 yards and two touchdowns in the 35-31 victory over the New England Patriots. Despite Dalton Kincaid's return in Week 14, Knox has dominated, totaling 130 yards and two touchdowns over his past two games. Knox played 70% of the snaps in Week 15, while Kincaid played only 34%. With his connection to star quarterback Josh Allen, Knox has starting value in Week 16. He faces a Browns defense that ranks middle-of-the-pack against tight ends this season. The door is open for Knox to have another big outing in Week 16, but he remains a low-end option with Kincaid in the picture.
December 20, 2025 11:02 AM EST
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