These are the top fantasy football players of the Buffalo Bills as ranked by Average Draft Position (ADP) in PPR-format mock drafts.
Data as of December 13, 2025.
| # | Name | Pos | Team | ADP | Bye |
|---|
| Week | Home/Away | Opponent |
|---|---|---|
| 1 | Home | Baltimore Ravens |
| 2 | Away | New York Jets |
| 3 | Home | Miami Dolphins |
| 4 | Home | New Orleans Saints |
| 5 | Home | New England Patriots |
| 6 | Away | Atlanta Falcons |
| 8 | Away | Carolina Panthers |
| 9 | Home | Kansas City Chiefs |
| 10 | Away | Miami Dolphins |
| 11 | Home | Tampa Bay Buccaneers |
| 12 | Away | Houston Texans |
| 13 | Away | Pittsburgh Steelers |
| 14 | Home | Cincinnati Bengals |
| 15 | Away | New England Patriots |
| 16 | Away | Cleveland Browns |
| 17 | Home | Philadelphia Eagles |
| 18 | Home | New York Jets |
Buffalo Bills running back James Cook has handled 83 carries over his last four games, totaling 388 rushing yards and one touchdown while adding 11 receptions for 143 yards and another score. The 26-year-old ranks second in the NFL with 1,308 rushing yards, averaging 5.3 yards per carry. Cook faces a formidable challenge against a Patriots defense that ranks third in the league, allowing just 89.5 rushing yards per game and five rushing touchdowns all season. New England surrendered just 49 yards on 15 carries to Cook in their Week 5 meeting. Despite the difficult matchup, Cook's workhorse role remains secure with Ray Davis and Ty Johnson serving as change-of-pace options behind him. His 20.8 carries per game over the last month demonstrate elite volume, though modest receiving usage limits PPR upside against a stingy Patriots front. Cook ranks as RotoBaller's RB10 in PPR formats for Week 15.
December 13, 2025 5:18 AM EST
Buffalo Bills quarterback Josh Allen enters Week 15 in elite form after posting 944 passing yards with seven touchdowns across his last four games while adding 176 rushing yards and five rushing touchdowns on the ground. The 29-year-old has been particularly dangerous in the red zone, accounting for 12 total touchdowns over the past month. Allen faces a Patriots defense that ranks middle-tier against opposing quarterbacks, allowing 220 passing yards per game and 23 touchdown passes through 14 games. The Bills' receiving corps has stabilized around Khalil Shakir, Gabe Davis, and Tyrell Shavers, with Dalton Kincaid expected back from his month-long absence. The matchup at Gillette Stadium sets up favorably for Allen's aggressive downfield approach, as New England's secondary has generated just six interceptions this season. Allen's dual-threat upside, combined with consistent volume, makes him a must-start, ranking as RotoBaller's QB1 for Week 15.
December 13, 2025 5:14 AM EST
Buffalo Bills wide receiver Joshua Palmer (ankle) was limited in practice all week and is considered questionable to play in Week 15 versus the division-rival New England Patriots on Sunday, according to Maddy Glab of BuffaloBills.com. Palmer last played for the Bills in Week 12. Even if the 26-year-old is cleared to play this weekend, fantasy managers in deeper leagues should keep him on their benches. Palmer just has not been involved enough in Buffalo's offense in his first year with the team, catching 18 passes for 272 yards and no touchdowns on 29 targets over eight games played. He has yet to find the end zone and has gone over 50 receiving yards in a game in 2025 only twice. If Palmer misses another game, Gabe Davis and Brandin Cooks have a better chance of contributing behind Khalil Shakir and Keon Coleman.
December 12, 2025 12:46 PM EST
Buffalo Bills wide receiver Joshua Palmer (ankle) is listed as a limited practice participant with an ankle injury for the second straight day on Thursday. Palmer has missed two consecutive games due to the ailment, and his status appears to be in question for Buffalo's critical Week 15 matchup against the New England Patriots. Across eight games played in 2025, the 26-year-old has recorded 18 receptions for 272 yards on 29 targets. While Palmer does not profile as a fantasy-relevant wideout even if active, his status could affect the target share and playing time for Bills wide receivers Khalil Shakir, Keon Coleman, and Tyrell Shavers. Unless he can practice in full on Friday, Palmer appears likely to head into the weekend with a questionable designation.
December 11, 2025 4:08 PM EST
Buffalo Bills wide receiver Joshua Palmer (ankle, knee) is listed as a limited participant in Wednesday's practice, ESPN's Alaina Getzenberg reports. Palmer has missed the past two games with injuries to his knee and ankle, in addition to missing several games earlier in the season. The 26-year-old hasn't been an impactful fantasy football option when he has played, recording 18 receptions for 272 yards on 29 targets in eight games. The former Los Angeles Chargers wideout appears to be trending in the right direction for a return in Week 15 against the New England Patriots, but he should only be considered a fantasy option in the deepest of leagues.
December 10, 2025 4:49 PM EST
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