These are the top fantasy football players of the Buffalo Bills as ranked by Average Draft Position (ADP) in PPR-format mock drafts.
Data as of October 21, 2025.
| # | Name | Pos | Team | ADP | Bye |
|---|
| Week | Home/Away | Opponent |
|---|---|---|
| 1 | Home | Baltimore Ravens |
| 2 | Away | New York Jets |
| 3 | Home | Miami Dolphins |
| 4 | Home | New Orleans Saints |
| 5 | Home | New England Patriots |
| 6 | Away | Atlanta Falcons |
| 8 | Away | Carolina Panthers |
| 9 | Home | Kansas City Chiefs |
| 10 | Away | Miami Dolphins |
| 11 | Home | Tampa Bay Buccaneers |
| 12 | Away | Houston Texans |
| 13 | Away | Pittsburgh Steelers |
| 14 | Home | Cincinnati Bengals |
| 15 | Away | New England Patriots |
| 16 | Away | Cleveland Browns |
| 17 | Home | Philadelphia Eagles |
| 18 | Home | New York Jets |
Through his team's first six games this season, Buffalo Bills running back Ray Davis has seen minimal usage. Davis has recorded just 48 yards from scrimmage and a touchdown on 16 total touches. After averaging 7.6 touches per game as a rookie in 2024, Davis is averaging 2.7 touches per game so far in 2025. Bills RB1 James Cook is currently dominating the early-down work in Buffalo, with veteran back Ty Johnson playing a role on passing downs. That leaves Davis on the outside looking in, barring an injury. Davis maintains some fantasy value as the handcuff option to Cook. Still, his standalone appeal is nonexistent if his usage remains the same when Buffalo returns to the field after its Week 7 bye.
October 21, 2025 10:01 PM EST
Buffalo Bills wide receiver Khalil Shakir broke out in his third year in the league in 2024 with career-highs across the board in catches (76), targets (100), and receiving yards (821), but it came with only four touchdowns in 15 regular-season games (nine starts). Going into Buffalo's Week 7 bye, Shakir had 25 receptions on 34 targets for 268 yards and two touchdowns in six games. He scored in back-to-back games in Weeks 3 and 4, but he has not exceeded 70 receiving yards in a contest this year, while the Bills continue to spread the ball around in the passing attack. In half-PPR scoring, Shakir is just inside the top 50 wideouts with 8.6 points per game. Although the 25-year-old is one of the top wideouts in the Bills' offense, he's not a great fit in an offense that relies on power more than anything, and he's rarely targeted in the red zone. Fantasy managers might want to expect another quiet game this Sunday against a Carolina Panthers defense that has been much-improved in 2025 against the pass.
October 21, 2025 7:55 PM EST
Since Buffalo Bills second-year wide receiver Keon Coleman had an eight-catch, 112-yard, one-touchdown performance in the season opener against the Baltimore Ravens, he has 16 catches for 125 yards and one touchdown on 24 targets in five games. He was benched at the start of the Week 5 loss to the New England Patriots for disciplinary reasons and has seven grabs for only 34 yards and a touchdown in the last two games. During the bye last week, Coleman tweeted "Say Less" with a handshake emoji, but deleted it almost immediately. It's unclear what exactly the 22-year-old meant by it, but fantasy managers are just wondering if he'll be able to turn it around in Week 8 against the Carolina Panthers. Coleman hasn't shown much chemistry with quarterback Josh Allen, and it wasn't a good sign that he couldn't make an impact in Week 6 with tight end Dalton Kincaid and receiver Curtis Samuel out due to injuries. Maybe the Bills will force the issue with Coleman coming out of their bye, but it's hard to recommend him as a flex play against a Carolina defense that has been stingy against opposing receivers in terms of fantasy points this year.
October 21, 2025 7:41 PM EST
Buffalo Bills head coach Sean McDermott said on Tuesday that wide receiver Joshua Palmer (ankle) is "week-to-week" after he suffered an ankle injury in the Monday night loss to the Atlanta Falcons and was unable to return, according to The Athletic's Joe Buscaglia. Palmer injured his ankle in the first half of Monday night's contest when he was tackled awkwardly, and he was unable to return to the game. He finished with two catches for 60 yards. Buffalo's bye in Week 7 is coming at a good time for Palmer, but his week-to-week designation means he won't be a lock to be ready when the Bills return to action on Oct. 26 in Week 8 against the Carolina Panthers. The 26-year-old has failed to stand out in his first year in Buffalo in an offense that continues to spread the ball around. Palmer has only 14 catches on 20 targets for 234 yards and no scores in six games. He'll be a popular drop candidate by fantasy managers with the Bills on bye in Week 7.
October 14, 2025 5:42 PM EST
Buffalo Bills head coach Sean McDermott said on Tuesday that tight end Dalton Kincaid (oblique), who did not play in the Monday night loss to the Atlanta Falcons in Week 6, is "day-to-day," according to Joe Buscaglia of The Athletic. Additionally, veteran wide receiver Curtis Samuel (neck, ribs) is also considered day-to-day. Kincaid's injury isn't very serious, which is great news, especially with the Bills on their bye in Week 7. It means that both Kincaid and Samuel should be ready to go when the team returns to action in Week 8 to face the Carolina Panthers on the road on Oct. 26. Buffalo's offense struggled on Monday night against an improved Atlanta defense without Kincaid in the mix. Backup Dawson Knox found the end zone for the first time this year on Monday with Kincaid out, but it was his only catch of the game on just two targets. Fantasy managers looking for TE reinforcements going forward should probably avoid Knox.
October 14, 2025 5:35 PM EST
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