Who Should I Start? Alvin Kamara or James Cook

Sunday, October 12, 12:01 PM

New Orleans Saints running back Alvin Kamara (ankle) is officially active for Sunday's Week 6 contest against the New England Patriots. He had been listed as questionable after being a limited participant in practice. The veteran running back has remained a productive ball carrier and pass catcher in his age-30 season, but we've started to see the Saints opt for somewhat of a split between him and Kendre Miller lately. Kamara's eight receptions over the last two games keep him in the high-end RB3/flex range for fantasy football, but he's no longer a top-tier workhorse. That is especially true against a Patriots defense that has allowed the sixth-fewest fantasy points to running backs in 2025.

Saturday, October 11, 1:46 PM

Buffalo Bills running back James Cook will face one of his toughest challenges of the season when he takes on Atlanta's sixth-ranked run defense on Monday night. The Falcons have excelled at controlling time of possession and limiting offensive opportunities, though they've allowed a 44.7% scoring rate on drives, leaving the door open for Cook to find the end zone. The third-year back is averaging 107.8 scrimmage yards and one touchdown per game, but he's coming off a sluggish performance against New England's opportunistic defense. While Cook's volume and role in Buffalo's high-powered offense keep him in RB1 territory, fantasy managers should temper expectations--his Week 6 success will likely hinge on finding pay dirt against a disciplined Falcons front.