Who Should I Start? Brandon Aiyuk or Jauan Jennings

Tuesday, August 26, 5:06 PM

The San Francisco 49ers officially placed wide receiver Brandon Aiyuk (knee) on the Reserve/Physically Unable to Perform list to begin the 2025 season, which means he will miss at least the first four contests. Head coach Kyle Shanahan has already said that Aiyuk might be targeting a return around Week 6 on the road against the Tampa Bay Buccaneers. The 27-year-old suffered a torn ACL and MCL in Week 7 of last season, which is why he's not ready for the start of 2025. The former first-round wideout had been a major disappointment in fantasy before his season-ending knee injury, too, as he caught just 25 of 47 targets for 374 yards and didn't find the end zone once in seven games. It's understandable for fantasy managers to want to avoid him altogether this year, although he's still worth drafting in leagues with IR spots. With Aiyuk sidelined, Jauan Jennings (calf) and Ricky Pearsall should serve as the top wideouts in San Fran.

Sunday, September 7, 6:52 PM

San Francisco 49ers wide receiver Jauan Jennings (shoulder) is uncertain to return to the field for Sunday's season opener against the Seattle Seahawks. Jennings was forced to exit the game with a shoulder injury in the second half. His absence is certainly a blow with George Kittle (hamstring) also banged up. If Jennings doesn't return, he'll end his day with two receptions on five targets for 16 yards. The 49ers don't have a ton of depth at wideout right now. Ricky Pearsall, Skyy Moore, and Russell Gage would all likely see increased roles if Jennings misses time.