Who Should I Start? Christian McCaffrey or Alvin Kamara

Sunday, September 7, 10:07 AM

San Francisco 49ers running back Christian McCaffrey (calf) did not practice on Friday, but he was a "big participant in the walkthrough on Saturday," according to NFL Network's Ian Rapoport. As a result, the star running back is trending toward playing. Fantasy managers are holding their breath and hoping that McCaffrey avoids a repeat of the 2024 season when he was expected to be healthy for Week 1 but then ultimately missed the first nine games. We'll get confirmation on his status around 2:35 p.m. ET when the 49ers post their list of inactive players. If McCaffrey does suit up against the Seahawks, he'll rank as a mid-range RB1 in fantasy football.

Saturday, September 6, 10:26 AM

It's no surprise that New Orleans Saints running back Alvin Kamara is locked in as the Saints' lead back ahead of Kendre Miller and rookie Devin Neal. Despite coaching changes, offensive line struggles, and shaky quarterback play, Kamara has averaged over 1,440 total yards and 10 touchdowns per season across eight years. The Saints' offense is likely to run through him, with Kamara handling the bulk of carries and seeing heavy involvement in the passing game. At 30, he enters the "dreaded" age for running backs, and it remains to be seen if his production as a pass-catcher will start to decline. With second-year QB Spencer Rattler under center, the offense as a whole is questionable, but Kamara profiles as a high-upside RB2 for Week 1 against the Cardinals.