Who Should I Start? Christian McCaffrey or James Cook

Thursday, February 5, 5:06 PM

San Francisco 49ers running back Christian McCaffrey was named the 2025 Comeback Player of the Year on Thursday night, according to Matt Barrows of The Athletic. McCaffrey was limited to only four games in 2024 due to Achilles and knee issues, but he played in all 17 regular-season games in 2025 and led the 49ers in both rushing (1,202) and receiving yards (924). The four-time Pro Bowler and three-time first-team All-Pro handled a career-high 311 carries and scored 10 rushing touchdowns while also catching 102 passes on 129 targets with an additional seven trips to the end zone as a receiver. The Offensive Player of the Year in 2023 was the RB1 in half-PPR fantasy scoring this year after he slipped to the late first round of many drafts following his injury-plagued 2024 campaign. CMC is entering his age-30 campaign and has a lengthy injury history, but it's simply too hard to ignore his game-changing dual-threat abilities out of the backfield as the engine of San Fran's offense.

Tuesday, January 13, 7:00 PM

After finishing the regular season with an NFL-best 1,621 rushing yards, Buffalo Bills running back James Cook had an underwhelming outing in his first game of the postseason. The 26-year-old was held to just 46 rushing yards on 15 carries and five receiving yards on two catches by the Jacksonville Jaguars. Cook's regular-season track record should afford him the benefit of the doubt from fantasy managers. However, he will face another very difficult run defense in the Divisional round when Buffalo travels to Denver to take on the Broncos. The Broncos defense finished the regular season ranked third in the NFL in yards per carry allowed (3.9) and tied for fourth in rushing touchdowns allowed (11). Additionally, Buffalo's already depleted pass-catching corps lost another two wide receivers in Gabe Davis (knee) and Tyrell Shavers (knee), who both suffered season-ending knee injuries in the Wild Card round. As a result, Denver could be even more geared up to stop Cook and take away the run. Cook remains a high-end running back option, but fantasy managers may want to downgrade expectations heading into the Divisional round.