Who Should I Start? Christian McCaffrey or James Cook

Sunday, November 16, 8:42 PM

San Francisco 49ers running back Christian McCaffrey had 13 carries for 81 rushing yards and two rushing touchdowns during Sunday's Week 11 win over the Arizona Cardinals. He also caught five of his six targets for an additional 40 receiving yards and one receiving touchdown. The superstar running back continues to demonstrate excellence as a rusher and receiver, and his big game officially propelled him past Jonathan Taylor for the overall RB1 spot (PPR) through 11 weeks. Given that he was a late-first-round pick in most redraft leagues this year, managers are getting even more than they expected from the 29-year-old. He remains a must-start RB1 for Week 12 against his old team, the Carolina Panthers.

Sunday, November 16, 10:34 PM

Buffalo Bills running back James Cook wasn't very efficient on the ground in Sunday's 44-32 win over the visiting Tampa Bay Buccaneers in Week 11, but he still managed to go over 100 scrimmage yards while securing his first receiving touchdown of the year. Cook had 16 rushing attempts for 48 yards on the ground (3.0 yards per carry) while adding three catches on three targets for a season-high 66 yards through the air and his first receiving TD (eighth total in 2025). The 26-year-old had a tough time finding space to run on Sunday against a stout Buccaneers defensive front, but he salvaged his day for fantasy managers by contributing as a pass-catcher, finishing as Buffalo's second leading receiver. Cook's TD came on a 25-yard reception. He's a must-start in all fantasy formats, but Cook might need more contributions as a pass-catcher again in Week 12 in a tough matchup on the ground against the Houston Texans on Thursday Night Football.