Who Should I Start? Christian McCaffrey or TreVeyon Henderson

Saturday, November 22, 5:26 AM

San Francisco 49ers running back Christian McCaffrey was the overall RB1 in Week 11, his third such finish in the last five weeks and his tenth top-10 finish in 2025. McCaffrey is in a good spot to attempt a repeat against the Carolina Panthers on Monday night. Much of McCaffrey's production in 2025 has come as a pass-catcher, but with Carolina offering up 4.72 yards per carry to opposing running backs this season, there is reason to believe he will do more damage on the ground than usual in Week 12. Carolina has been especially bad over the last four weeks, giving up a league-worst six rushing touchdowns and the fourth-most fantasy points per game to running backs. It goes without saying that McCaffrey should be in starting lineups in Week 12, but fantasy football managers are justified in feeling especially optimistic about what the superstar will produce in his first game against his former team.

Sunday, November 23, 5:42 PM

New England Patriots running back TreVeyon Henderson rushed for 66 yards on 18 carries during Sunday's Week 12 contest against the Cincinnati Bengals. He also caught three of his four targets for an additional 15 receiving yards. There was some concern about Henderson's role with Rhamondre Stevenson returning from injury. While Stevenson did earn some touches, Henderson remained the primary running back. Now that he has the lead role all to himself, the rookie needs to turn his attention to improving his efficiency. He averaged 3.7 yards per carry on Sunday, just one game removed from averaging 3.3 yards per carry against the Jets. If he can improve his scoring or yardage efficiency, he can be an RB1 going forward. In the meantime, he ranks as more of a mid-range RB2 for Week 13 against the New York Giants.