Who Should I Start? DeVonta Smith or Brandon Aiyuk

Friday, September 22, 7:13 PM

Philadelphia Eagles wide receiver DeVonta Smith (hamstring, thigh) was listed as a limited practice participant for a second straight day on Friday. Smith apparently picked up several injuries in last Thursday's win over the Minnesota Vikings when he went off for four catches on five targets for 131 yards and a touchdown. Neither injury seems to be very serious, though, so the 24-year-old pass-catcher isn't in any real danger of sitting out of Monday's clash with the Tampa Bay Buccaneers on the road. A.J. Brown could get the squeaky wheel treatment in that one, but Smith remains a must-start in fantasy lineups as long as he's active. Through his first two games, he has 11 receptions on 15 targets for 178 yards and two touchdowns for the Eagles.

Thursday, September 21, 7:13 PM

San Francisco 49ers wide receiver Brandon Aiyuk (shoulder) is officially inactive for the Thursday night game against the New York Giants. Aiyuk suffered a shoulder injury in the Week 2 win over the Los Angeles Rams, but he avoided a broken collarbone after undergoing a CT scan on Monday. The good news is that this doesn't appear to be a long-term injury for Aiyuk, but the Niners aren't going to put him in harm's way on a short week early in the season. For now, fantasy managers should consider him questionable to play in Week 4 against the Arizona Cardinals. In his absence on Thursday night, Deebo Samuel and George Kittle should see more targets, while Jauan Jennings and rookie Ronnie Bell will compete for No. 3 duties in San Fran.