Who Should I Start? James Conner or Miles Sanders

Saturday, September 30, 1:36 AM

Arizona Cardinals running back James Conner faces tough sledding this week against the San Francisco 49ers. Last week against the Dallas Cowboys, Conner carried the ball 18 times for 98 yards and a touchdown. Even though Conner is currently fourth best in the league in explosive run rate, San Francisco is an elite run defense. They have yielded the seventh-lowest explosive run rate, the sixth-lowest missed tackles allowed rate, and the fourth-lowest yards after contact per attempt. With Arizona also having a weak offensive line, the possibility exists the 49ers will stack the box against Conner and force quarterback Joshua Dobbs to beat them. Even though Conner has been solid at the RB position so far, he's at best an RB2 for this week's matchup.

Friday, September 29, 1:14 PM

Carolina Panthers running back Miles Sanders (groin) didn't practice on Friday and is now questionable to play in Week 4 against the Minnesota Vikings on Sunday. Sanders was downgraded at Friday's practice after he was limited on both Wednesday and Thursday. The 26-year-old could be a true game-time decision, so fantasy managers will want to check the Sunday morning inactives to see if he's playing in Week 4. If Sanders is out or limited at all, Chuba Hubbard would step in as Carolina's primary backfield option. And with rookie quarterback Bryce Young (ankle) returning from a one-game absence, the Panthers could very well lean on their ground game as much as possible if game script allows it. For what it's worth, the Panthers are optimistic that Sanders will play.