Who Should I Start? James Cook or Isaac Guerendo

Tuesday, May 27, 1:04 PM

NFL Network' Cameron Wolfe reports that every Buffalo Bills player is present for organized team activities on Tuesday except for running back James Cook, who is seeking a new long-term contract extension. We're still in the voluntary portion of the offseason schedule, so Cook won't be fined, but the 25-year-old wants the team to reward him with an extension as he heads into the final year of his rookie deal. The next change for Cook to show up will be for mandatory minicamp, which runs from June 10-12. It's unclear if Cook plans on holding out into training camp this summer if he doesn't have a new contract by then, but if he reports and is active for Week 1 of the 2025 regular season, he'll be Buffalo's clear RB1 after his second straight 1,000-yard rushing season and a league-high 16 rushing TDs in 2024. Fantasy managers should expect TD regression for the two-time Pro Bowler.

Monday, January 6, 10:31 PM

An MRI exam on Monday morning revealed that San Francisco 49ers rookie running back Isaac Guerendo (ankle, knee) suffered an MCL sprain and an ankle sprain in the loss to the division-rival Arizona Cardinals on Sunday in the Week 18 regular-season finale, according to a source. Guerendo will have plenty of time to heal up in the offseason, and the best news is that he didn't suffer any damage to his ACL. Both of the injuries are to his left leg. The 24-year-old fourth-round pick didn't see much of an opportunity in 2024 until late in the season when both Christian McCaffrey (knee) and Jordan Mason (ankle) were ruled out for the year, but when he did get his chances, he was pretty effective out of the Niners' backfield. Guerendo finished with 5.0 yards per carry for 420 yards and four TDs on 84 carries through 16 games. He should serve as valuable insurance for McCaffrey in 2025.