Who Should I Start? James Cook or Isaac Guerendo


Week 1 Projections

Fant.
Pts.
Rush.
Yds.
Rush
TD
Rec. Rec.
Yds.
Rec
TD
0.0 0.0 0.0 0.0 0.0 0.0

James Cook News

James Cook Continues to Trend Up Every Year

Monday, April 6, 6:23 PM

Buffalo Bills running back James Cook has been trending up in fantasy football year after year. He opened his career as the RB44 as a rookie in 2022, but he has been a top-12 fantasy running back every season since then. He jumped to the ranking of overall RB6 last year, carrying the Bills' offense with 1,621 rushing yards, 291 receiving yards, and 14 touchdowns. Before the season, critics forecasted touchdown regression for Cook. While his touchdown total did scale back slightly from 18 to 14, he was still highly productive around the goal line, and he handled a new career-high rushing workload. The Bills underwent a coaching staff shakeup during the offseason, but new head coach Joe Brady was formerly Buffalo's offensive coordinator, so we don't expect the offense to look too different next year. Cook should continue to operate as the every-down back, rarely ceding touches to Ty Johnson and Ray Davis. He continues to have top-five upside in redraft and dynasty formats.


Week 1 Projections

Fant.
Pts.
Rush.
Yds.
Rush
TD
Rec. Rec.
Yds.
Rec
TD
0.0 0.0 0.0 0.0 0.0 0.0

Isaac Guerendo News

Isaac Guerendo a Drop Candidate in Dynasty Leagues?

Wednesday, February 18, 10:02 AM

San Francisco 49ers running back Isaac Guerendo has emerged as a potential drop candidate as dynasty managers prepare for the offseason roster crunch. Between clearing taxi squad spots, adding players, and navigating rookie drafts, dynasty managers may need to make decisions about which rostered players to cut. Guerendo is a prime candidate after an underwhelming second season with the 49ers in 2025. He appeared in 14 games but played exclusively on special teams, never logging an offensive snap. He was buried on the depth chart behind Christian McCaffrey, Brian Robinson Jr., Jordan James, and even fullback Kyle Juszczyk. It was a surprising, harsh development for the Louisville product after he finished as the overall RB48 in PPR leagues with 572 scrimmage yards and five touchdowns in 2024. Evidently, the 49ers don't see Guerendo in their long-term plans, and it's hard to imagine he'll climb the depth chart in 2026, even with Robinson expected to hit free agency. Managers in most dynasty leagues should feel comfortable dropping the 25-year-old.


James Cook vs. Isaac Guerendo

Still trying to decide between Cook and Guerendo? Check on the latest news to make sure both players are active and healthy. Our PPR projections show that James Cook is projected to score 0.0 points this week while Isaac Guerendo is projected to score 0.0 points.