| Age | 25 |
|---|---|
| Birthdate | June 28, 2000 |
| Height | 6'0" |
| Weight | 221 lb |
| College | Louisville | |
|---|---|---|
| Year | 2024 | |
| Pick | Round: 4, Overall: 129 | |
| Team | SF |
| Week 1 Projections | ||
|---|---|---|
| Carries | Yards | Touchdowns |
| 4.47 | 17.73 | 0.15 |
You can see where those projections compare to other RBs in our Running Back Rankings.
San Francisco 49ers running back Isaac Guerendo (shoulder) played at less than 100 percent during Saturday's preseason contest. Guerendo started the game, but re-aggravated his shoulder injury in the first quarter. Luckily, Guerendo was able to return to the game after getting looked at on the sideline. At the moment, all signs point to Guerendo being available for the season opener. However, his fantasy value is going to take a serious hit with Brian Robinson Jr. taking over as the RB2 in San Francisco. Guerendo probably won't see significant snaps unless someone gets hurt in the backfield.
Aug. 24, 2025 8:27 AM EST
| YEAR | TM | GM | Rushing | Receiving | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ATT | YDS | YPC | TD | FUM | REC | TGT | % | YDS | TD | YPC | |||
| 2024 | SF | 16 | 82 | 415 | 5.1 | 4 | 1 | 15 | 16 | 93.8 | 152 | 0 | 10.1 |
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