Isaac Guerendo

San Francisco 49ers
Running Back #31

Personal

Age	25
Birthdate	June 28, 2000
Height	6'0"
Weight	221 lb

Draft

College	Louisville
Year	2024
Pick	Round: 4, Overall: 129
Team	SF

Fantasy Value

You can see where his value compares to other RBs in our Running Back Rankings.

Player News

Isaac Guerendo: Isaac Guerendo Buried on Depth Chart, Looking for New Team?

The Athletic's Vic Tafur writes that San Francisco 49ers running back Isaac Guerendo, who was a fourth-round pick in 2024, "seems like he is buried" and will be "looking for a new team." The 49ers say that they will be looking to give Christian McCaffrey fewer touches in 2026, which is why they drafted rookie Kaelon Black in the third round. The Niners also have Jordan James, Patrick Taylor Jr., and Sincere McCormick in their RB room, leaving little playing time left for Guerendo. Black is expected to compete with James for the No. 2 role, so the 25-year-old Guerendo figures to be the RB4 in San Fran right now, at best. Guerendo carried the ball 84 times for 420 yards (5.0 yards per carry) and four touchdowns while adding 15 receptions for 152 yards through the air in 16 regular-season games (three starts), but he didn't see a single carry in 14 regular-season contests in Year 2 in 2025. He appears to be the odd-man out, making him a cut candidate in dynasty/keeper leagues going into the 2026 campaign.

May. 5, 2026 9:37 AM EST