Who Should I Start? James Cook or Omarion Hampton

Saturday, October 11, 1:46 PM

Buffalo Bills running back James Cook will face one of his toughest challenges of the season when he takes on Atlanta's sixth-ranked run defense on Monday night. The Falcons have excelled at controlling time of possession and limiting offensive opportunities, though they've allowed a 44.7% scoring rate on drives, leaving the door open for Cook to find the end zone. The third-year back is averaging 107.8 scrimmage yards and one touchdown per game, but he's coming off a sluggish performance against New England's opportunistic defense. While Cook's volume and role in Buffalo's high-powered offense keep him in RB1 territory, fantasy managers should temper expectations--his Week 6 success will likely hinge on finding pay dirt against a disciplined Falcons front.

Sunday, October 12, 9:16 AM

Los Angeles Chargers running back Omarion Hampton (ankle) is expected to spend more than the minimum four weeks on injured reserve, according to Mike Garafolo of NFL Network. The injury that the rookie suffered in Week 5 appears to be serious enough that he'll be out through at least Week 10, and perhaps longer. The Chargers have a Week 12 bye, so it wouldn't be surprising to see Los Angeles hold him out until Week 13, giving him an extra week off to rest. Losing both Hampton and Najee Harris (Achilles) is a major blow for the Chargers, who will turn to Hassan Haskins and Kimani Vidal but could also look to make external running back additions.