Who Should I Start? Joe Mixon or Isaac Guerendo

Friday, May 30, 8:41 PM

Houston Texans running back Joe Mixon (foot) did not participate in voluntary OTA workouts on Friday. Mixon is currently in a walking boot, but it's reportedly not a serious injury. The star running back played through an ankle injury in the playoffs, so maybe it's not 100 percent healed yet. Regardless, fantasy managers shouldn't be concerned as Mixon should be ready to go in time for training camp. The Texans aren't going to push Mixon onto the field this early into camp when he's not fully healthy. This minor injury shouldn't impact his status on draft boards.

Monday, January 6, 10:31 PM

An MRI exam on Monday morning revealed that San Francisco 49ers rookie running back Isaac Guerendo (ankle, knee) suffered an MCL sprain and an ankle sprain in the loss to the division-rival Arizona Cardinals on Sunday in the Week 18 regular-season finale, according to a source. Guerendo will have plenty of time to heal up in the offseason, and the best news is that he didn't suffer any damage to his ACL. Both of the injuries are to his left leg. The 24-year-old fourth-round pick didn't see much of an opportunity in 2024 until late in the season when both Christian McCaffrey (knee) and Jordan Mason (ankle) were ruled out for the year, but when he did get his chances, he was pretty effective out of the Niners' backfield. Guerendo finished with 5.0 yards per carry for 420 yards and four TDs on 84 carries through 16 games. He should serve as valuable insurance for McCaffrey in 2025.