Who Should I Start? Joe Mixon or Kyren Williams

Thursday, November 20, 12:34 PM

Houston Texans running back Joe Mixon (ankle, foot) is not expected to play this season as he deals with a foot injury from the offseason, according to Ian Rapoport of NFL Network. Mixon will likely stay on the Physically Unable to Perform list through the end of the 2025 season, while the Texans move forward with veteran Nick Chubb and rookie Woody Marks in their backfield. Things had been trending this way for a while, as the Texans haven't been giving any real updates on Mixon for pretty much the entire season. Fantasy managers who are still stashing the 29-year-old in redraft leagues should send him to the waiver wire now. Mixon's injury dates all the way back to spring workouts. One would think he'd be ready for the start of the 2026 campaign, but there has been little information about the exact nature of his injury. Marks, a fourth-rounder in April, has slowly started to see more work and should be the backfield leader over Chubb by the end of the year.

Thursday, December 18, 1:36 AM

Los Angeles Rams running back Kyren Williams has been terrific lately, and he'll look to extend his bout of success (as well as his three-game touchdown streak) during Thursday's Week 16 contest against the Seattle Seahawks. The Rams have made a significant effort to reduce Williams' workload so that he stays fresh for the playoffs, but even so, he has continued to operate as a mid-to-low RB1 in fantasy football. Over his last three games, he has 234 rushing yards, 23 receiving yards, and four total touchdowns. He owns a phenomenal average of 5.7 yards per carry during that span, and he's the overall RB9 in PPR leagues through 14 games this season. If Williams keeps up this pace, he'll be a top-10 fantasy running back for the third consecutive year. The 25-year-old's ability to produce on a slightly reduced workload has been terrific for fantasy managers, and that trend should continue in Week 16. While the Seahawks have allowed the third-fewest fantasy points to running backs in 2025, Williams has shown that he is matchup-proof. In fact, when he faced the Seahawks just five weeks ago, he had 91 rushing yards and a touchdown. He ranks as the overall RB16 in RotoBaller's latest fantasy rankings, but there's no doubt that he has top-12 upside. He should be started in all leagues ahead of Thursday Night Football in Week 16.