Who Should I Start? Josh Jacobs or Kyren Williams

Saturday, November 8, 5:09 PM

Green Bay Packers running back Josh Jacobs (not injury-related) is off this week's injury report and good to go as the Packers host the Philadelphia Eagles in Week 10. Jacobs has been scoring touchdowns at will this season, with eight touchdowns in his last five games. That touchdown volume has helped buoy some of Jacobs' lack of efficiency on a per-rush basis this season. He's been a top-20 fantasy running back every week this season but Week 2, where he was RB21. Jacobs has been a bit banged up lately with a nagging calf injury, but that hasn't stopped him from playing. His workload has been a bit more managed with backups Emanuel Wilson and Chris Brooks seeing some touches in recent weeks, but as long as Jacobs is getting the red-zone touches, everything is great. It's a tough matchup at home against the Eagles' defensive front, but lock in Jacobs as an RB1 this week.

Saturday, November 8, 2:19 PM

Los Angeles Rams running back Kyren Williams remains a must-start fantasy option in Week 10 against the San Francisco 49ers as he looks to build on a successful first half of the 2025 season. Williams has 586 rushing yards, 166 receiving yards, and six touchdowns so far, ranking as the overall RB13 in PPR leagues. On paper, a matchup against the 49ers could pose a challenge for running backs, as San Francisco ranks near the middle of the league in fantasy points allowed to the position. They've also surrendered the seventh-fewest rushing touchdowns to running backs. However, Williams didn't see that level of shutdown defense when the 49ers faced the Rams in Week 5. During that matchup, the 25-year-old had 14 carries, 65 rushing yards, eight catches, 66 receiving yards, and two receiving touchdowns. His 32.1 points (PPR) represented a season-high. Williams will look to repeat his success against a banged-up 49ers defense this week, and he should continue to be deployed as an RB1 in most leagues.