Who Should I Start? Kendre Miller or Isaac Guerendo

Friday, January 3, 3:28 PM

New Orleans Saints running back Kendre Miller (concussion) didn't practice all week and has been ruled out for the Week 18 regular-season finale on Sunday against the division-rival Tampa Bay Buccaneers after he suffered a concussion in the Week 17 loss to the Las Vegas Raiders. Alvin Kamara (groin) is doubtful to play as well, which means Clyde Edwards-Helaire could lead the Saints' backfield against the Bucs this weekend, with veteran Jamaal Williams and Jordan Mims also pitching in. The 22-year-old Miller dealt with more injuries in his sophomore season in the NFL after playing in only eight games as a rookie in 2023. The former TCU product played in just eight games in 2024 and had 39 rushing attempts for 148 yards and one touchdown, adding five catches for 33 yards. Miller's standing in the organization has likely soured after two injury-filled years to begin his career.

Monday, January 6, 10:31 PM

An MRI exam on Monday morning revealed that San Francisco 49ers rookie running back Isaac Guerendo (ankle, knee) suffered an MCL sprain and an ankle sprain in the loss to the division-rival Arizona Cardinals on Sunday in the Week 18 regular-season finale, according to a source. Guerendo will have plenty of time to heal up in the offseason, and the best news is that he didn't suffer any damage to his ACL. Both of the injuries are to his left leg. The 24-year-old fourth-round pick didn't see much of an opportunity in 2024 until late in the season when both Christian McCaffrey (knee) and Jordan Mason (ankle) were ruled out for the year, but when he did get his chances, he was pretty effective out of the Niners' backfield. Guerendo finished with 5.0 yards per carry for 420 yards and four TDs on 84 carries through 16 games. He should serve as valuable insurance for McCaffrey in 2025.