Who Should I Start? Kyler Murray or Khalil Shakir

Saturday, October 11, 9:58 PM

According to NFL Media's Ian Rapoport, the Arizona Cardinals "are leaving the door open" for Kyler Murray (foot) to suit up on Sunday versus the Colts. However, the team is realistically "preparing" for Jacoby Brissett to start in Week 6, although a final decision won't come until Sunday morning. The signal-caller is reportedly dealing with a "mid-foot sprain," with Rapoport adding that it's "a version of a Lisfranc injury." Unfortunately, that could sideline Murray for more than just one week. As far as Brissett is concerned, he's had some quality performances over the years. In 89 regular-season games, he's thrown for 11,400 yards, 53 touchdowns, and 24 interceptions, adding 15 more scores on the ground. With that said, Brissett has some value for managers in deeper Superflex formats despite a tough matchup on the horizon, especially with injuries at the quarterback position and a few teams getting the week off.

Saturday, October 11, 2:10 PM

Buffalo Bills wide receiver Khalil Shakir could see an uptick in targets Monday night with tight end Dalton Kincaid (oblique) questionable after limited practice participation this week. Shakir tied his season-high with nine targets in Week 5 and now sits tied for the team lead with 29 on the year, turning them into 235 receiving yards through five games. With the Bills set to face the NFL's top-ranked pass defense in Atlanta, Shakir will need to create separation against cornerbacks Mike Hughes and Dee Alford to stay productive. If Kincaid is ruled out, Shakir should serve as a reliable safety valve for Josh Allen and could offer sneaky PPR value as a volume-based WR3 or flex play in Week 6.