Who Should I Start? Matthew Stafford or Lamar Jackson

Saturday, November 8, 2:08 PM

Los Angeles Rams quarterback Matthew Stafford is having one of the best seasons of his career, and he remains a must-start fantasy quarterback in Week 10 against the San Francisco 49ers despite his limited rushing upside. Stafford now has 16 touchdowns and zero interceptions over his last five games, leading the Rams to a 6-2 start while supporting big fantasy performances from Puka Nacua, Davante Adams, and Kyren Williams. Stafford himself is the overall QB9 so far, and he's fourth in the MVP race with +500 odds. He has become matchup-proof this season and should be started against all opponents. With that said, a matchup against the San Francisco 49ers certainly doesn't hurt. The Niners have allowed the ninth-most fantasy points to opposing quarterbacks in 2025 and have forced just one interception. Stafford racked up 389 yards and three touchdowns when he faced the 49ers earlier this season.

Saturday, November 8, 9:21 AM

Baltimore Ravens quarterback Lamar Jackson returned from a three-game absence and picked apart the Miami Dolphins for four touchdowns through the air with a 78.3 completion percentage. He'll have a tougher task ahead of him in Week 10 against the Minnesota Vikings. They're around the middle of the pack in terms of fantasy points allowed to opposing QBs, with an average of 16.62 per game. Over the last three weeks, however, the Vikings have given up 19 or more fantasy points in each game. Jackson is already a must-start, and should continue to roll while the offense is the healthiest it's been all season.