Free agent wide receiver Andy Isabella inked a deal with the San Francisco 49ers on Thursday. The 49ers will technically be Isabella's fifth team in the NFL after bouncing around practice squads for the past few years. Isabella will add extra depth with injuries seemingly popping up left and right in the 49ers' wide receiver room. The former 62nd overall pick of the 2019 draft has put up career stats of 33 receptions for 447 yards and three touchdowns. After compiling the majority of these statistics during his first two years in the league with the Arizona Cardinals, Isabella will look to revamp his career in San Francisco.
Jul 31, 2025 6:25 PM EST
Veteran free-agent wide receivers Andy Isabella and Marquez Callaway signed with the San Francisco 49ers on Thursday, reported by NFL Network's Mike Garafolo. Isabella was a second-round pick in the 2019 NFL Draft by the Arizona Cardinals before a disappointing four-year career with the organization. He has not played in a game since 2022. Callaway went undrafted in 2020 out of the University of Tennessee and has tallied 83 receptions for 1,069 yards and seven touchdowns in 42 career games (all with Saints). The 49ers wideout group is thin during training camp as Jauan Jennings (calf) and Brandon Aiyuk (knee) miss time with injuries, so these are likely pure depth signings more than anything else. Either newly signed wideout entering the fantasy football radar in 2025 would be a surprise.
Jul 31, 2025 3:16 PM EST
The Buffalo Bills re-signed wide receiver Andy Isabella to their practice squad on Wednesday, according to a league source. Isabella was cut on Tuesday with the team getting their roster down to 53 players, but he will return the very next day to serve as extra receiver depth in Buffalo for the start of the 2023 regular season. The former second-round pick of the Arizona Cardinals in 2019 out of Massachusetts spent time with both the Cardinals and Baltimore Ravens last year, catching only two passes for 21 yards in five games (zero starts). In his four NFL seasons, Isabella has 33 receptions on 54 targets for 447 yards and three touchdowns in 41 games (three starts).
Aug 30, 2023 5:33 PM EST
Buffalo Bills wide receiver Andy Isabella was released by the team ahead of Tuesday's roster cutdown deadline. Isabella signed on with the Bills after the Ravens released him in late July and there was an outside chance he could have cracked the Bills 53-man roster due to their lack of depth at the receiver position. Instead, they're going to roll with Trent Sherfield, Khalil Shakir, and Deonte Harty as their wideouts behind Stefon Diggs and Gabe Davis. All three receivers will likely get chances in the slot. Isabella will likely end up on some team's practice squad in the coming days.
Aug 29, 2023 6:59 PM EST
Isabella is signing with the Bills, Aaron Wilson of KPRC 2 Houston repors.
Jul 28, 2023 2:00 PM EST
Isabella was released by the Ravens on Tuesday, Field Yates of ESPN reports.
Jul 25, 2023 2:20 PM EST
Isabella reverted to Baltimore's practice squad Monday, per the NFL's official transaction log.
Jan 2, 2023 3:48 PM EST
Isabella suffered a thigh injury during Sunday's game against the Steelers.
Jan 1, 2023 7:19 PM EST
The Ravens elevated Isabella from their practice squad to the active roster ahead of Week 17's contest against the Steelers, Field Yates of ESPN reports.
Dec 31, 2022 4:30 PM EST
Isabella reverted to the Baltimore practice squad Monday.
Dec 26, 2022 9:06 PM EST
The Ravens elevated Isabella from the practice squad to the active roster ahead of Saturday's matchup with Atlanta, Field Yates of ESPN reports.
Dec 23, 2022 1:56 PM EST
Isabella signed with the Ravens' practice squad Monday, Jeff Zrebiec of The Athletic reports.
Oct 10, 2022 1:55 PM EST
Isabella has not been signed by the Ravens and remains a free agent ahead of Week 5, Howard Balzer of SI.com reports.
Oct 8, 2022 6:25 PM EST
The Ravens will sign Isabella to their practice squad, Doug Kyed of Pro Football Focus reports.
Oct 5, 2022 4:59 PM EST
The Cardinals released Isabella on Tuesday, Darren Urban of Arizona's official site reports.
Oct 4, 2022 1:13 PM EST
Isabella gathered in one of two targets for 11 yards during Sunday's 20-12 loss to the Rams.
Sep 27, 2022 7:19 PM EST
Isabella (back) practiced in full Wednesday, Tyler Drake of ArizonaSports.com reports.
Sep 21, 2022 4:29 PM EST
Isabella (back) has been ruled out for Sunday's game against the Raiders, Josh Weinfuss of ESPN.com reports.
Sep 16, 2022 10:26 AM EST
Isabella (back) isn't expected to play Sunday against the Raiders, Aaron Wilson of ProFootballNetwork.com reports.
Sep 16, 2022 7:52 AM EST
Isabella (back) is not practicing Thursday, Jose M. Romero of The Arizona Republic reports.
Sep 15, 2022 9:02 AM EST
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