These are the top fantasy football players of the San Francisco 49ers as ranked by Average Draft Position (ADP) in PPR-format mock drafts.
Data as of May 31, 2025.
| # | Name | Pos | Team | ADP | Bye |
|---|---|---|---|---|---|
| 1 | Christian McCaffrey | RB | SF | 1.10 | 14 |
| 2 | George Kittle | TE | SF | 5.02 | 14 |
| 3 | Jauan Jennings | WR | SF | 6.08 | 14 |
| 4 | Brock Purdy | QB | SF | 7.07 | 14 |
| 5 | Ricky Pearsall | WR | SF | 9.06 | 14 |
| 6 | Brandon Aiyuk | WR | SF | 10.08 | 14 |
| 7 | Isaac Guerendo | RB | SF | 13.07 | 14 |
| 8 | San Francisco Defense | DEF | SF | 13.10 | 14 |
| 9 | Jake Moody | PK | SF | 14.05 | 14 |
Christian McCaffrey's current ADP is 1.10, which is the 10th pick of the 1st round, and 10th selection overall.
George Kittle's current ADP is 5.02, which is the 2nd pick of the 5th round, and 49th selection overall.
Jauan Jennings's current ADP is 6.08, which is the 8th pick of the 6th round, and 67th selection overall.
Brock Purdy's current ADP is 7.07, which is the 7th pick of the 7th round, and 78th selection overall.
Ricky Pearsall's current ADP is 9.06, which is the 6th pick of the 9th round, and 101st selection overall.
Brandon Aiyuk's current ADP is 10.08, which is the 8th pick of the 10th round, and 115th selection overall.
Isaac Guerendo's current ADP is 13.07, which is the 7th pick of the 13th round, and 151st selection overall.
San Francisco Defense's current ADP is 13.10, which is the 10th pick of the 13th round, and 153rd selection overall.
Jake Moody's current ADP is 14.05, which is the 5th pick of the 14th round, and 161st selection overall.
| Week | Home/Away | Opponent |
|---|---|---|
| 1 | Home | New York Jets |
| 2 | Away | Minnesota Vikings |
| 3 | Away | Los Angeles Rams |
| 4 | Home | New England Patriots |
| 5 | Home | Arizona Cardinals |
| 6 | Away | Seattle Seahawks |
| 7 | Home | Kansas City Chiefs |
| 8 | Home | Dallas Cowboys |
| 10 | Away | Tampa Bay Buccaneers |
| 11 | Home | Seattle Seahawks |
| 12 | Away | Green Bay Packers |
| 13 | Away | Buffalo Bills |
| 14 | Home | Chicago Bears |
| 15 | Home | Los Angeles Rams |
| 16 | Away | Miami Dolphins |
| 17 | Home | Detroit Lions |
| 18 | Away | Arizona Cardinals |
There is still no official timeline for San Francisco 49ers Brandon Aiyuk's (knee) return in 2025, but general manager John Lynch expressed some optimism regarding his recovery from a torn ACL and MCL in his right knee that he suffered last October. "Brandon's tracking in a good way with his knee, and you've just got to kind of let that play out," Lynch said. "We're not going to put him out there until he's ready, but we're excited with our receiver group and where we're at." Aiyuk will most likely not be ready for the start of the 2025 regular season, but if he continues to make strides in his rehab, he could return sooner than later. Regardless, the 27-year-old's fantasy stock has taken a big hit after he caught just 25 passes for 374 yards and no touchdowns in seven games before his season-ending injury last year. Until Aiyuk is able to return, Jauan Jennings and Ricky Pearsall (hamstring) will be the team's top wideouts.
May 30, 2025 12:36 PM EST
San Francisco 49ers wide receiver Ricky Pearsall (hamstring) is dealing with a hamstring injury and likely won't return to practice until training camp at the end of July, according to head coach Kyle Shanahan. It doesn't sound like it's a serious injury for Pearsall, the but Niners won't take any chances with last year's first-rounder after he also dealt with hammy issues going into his rookie season in 2024. The 24-year-old pass-catcher then suffered a gunshot wound to his chest and didn't make his NFL debut until Week 7. He's expected to have a key role in the offense in his sophomore season with Deebo Samuel Sr. no longer in town and Brandon Aiyuk (knee) unlikely to be ready for the start of the season, but Pearsall is going to lose valuable reps this offseason to gain chemistry with quarterback Brock Purdy. Pearsall could still be ready for Week 1, but this news doesn't do anything to dispel the notion that Pearsall is injury-prone.
May 29, 2025 6:04 PM EST
San Francisco 49ers tight end George Kittle recently said he was impressed that wide receiver Jacob Cowing, who weighed 168 pounds at last year's scouting combine, added more weight in the offseason. Cowing also trained with quarterback Brock Purdy in Jacksonville and Arizona this offseason, signaling he wasn't happy with a 2024 rookie season in which he was used sparingly on offense. The 24-year-old only caught four passes last year, but The Athletic's Matt Barrows thinks he should be an asset on quick-hitters and jet sweeps that went to Deebo Samuel Sr. in recent years. The former fourth-rounder (135th overall) out of Arizona could have a bigger role early in the 2025 season with Brandon Aiyuk (knee) rehabbing an injury and Demarcus Robinson facing a potential suspension, but for now, Cowing will just be one to keep an eye on during training camp.
May 28, 2025 1:41 PM EST
The Athletic's Matt Barrows writes that San Francisco 49ers wide receiver Ricky Pearsall could be best positioned for a breakout season in 2025. Pearsall met up with quarterback Brock Purdy to work with him this offseason after missing six games as a rookie last year after being shot on Aug. 31. He also missed most of training camp with hamstring and shoulder injuries. Brandon Aiyuk (knee) could miss the start of the 2025 regular season, while Demarcus Robinson could be suspended due to a DUI incident in November. The Niners still have Jauan Jennings, but Pearsall, who excels against press coverage, would also have a big role in the passing attack. Pearsall had a 141-yard outing in Week 17 against the Detroit Lions last year and could be on the rise if his chemistry with Purdy has improved. The 24-year-old should be a top-three wideout for San Fran this year.
May 28, 2025 1:26 PM EST
San Francisco 49ers kicker Jake Moody struggled last year after returning from a high-ankle sprain. The former third-rounder changed his approach this offseason from taking three steps before a kick to just two, according to The Athletic's Vic Tafur. Because Moody missed nine of 20 field-goal attempts in the last nine games, forcing the Niners to bring in veteran kicker Greg Joseph to give Moody competition this year. Before getting injured last year, the 25-year-old made 13 of his first 14 field-goal tries before spraining his ankle in a Week 5 loss to the Arizona Cardinals when he tried to make a tackle on a kickoff. He missed the next three games and wasn't the same when he returned. Moody is now fully healthy and likes the way he's kicking the ball this offseason, so he'll be a bounce-back candidate as a starting fantasy kicker in 2025.
May 27, 2025 1:33 PM EST
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