These are the top fantasy football players of the San Francisco 49ers as ranked by Average Draft Position (ADP) in PPR-format mock drafts.
Data as of December 8, 2025.
| # | Name | Pos | Team | ADP | Bye |
|---|
| Week | Home/Away | Opponent |
|---|---|---|
| 1 | Away | Seattle Seahawks |
| 2 | Away | New Orleans Saints |
| 3 | Home | Arizona Cardinals |
| 4 | Home | Jacksonville Jaguars |
| 5 | Away | Los Angeles Rams |
| 6 | Away | Tampa Bay Buccaneers |
| 7 | Home | Atlanta Falcons |
| 8 | Away | Houston Texans |
| 9 | Away | New York Giants |
| 10 | Home | Los Angeles Rams |
| 11 | Away | Arizona Cardinals |
| 12 | Home | Carolina Panthers |
| 13 | Away | Cleveland Browns |
| 15 | Home | Tennessee Titans |
| 16 | Away | Indianapolis Colts |
| 17 | Home | Chicago Bears |
| 18 | Home | Seattle Seahawks |
San Francisco 49ers wide receiver Ricky Pearsall has not had the second-year breakout that many were predicting back in training camp. Injuries have been a big issue yet again, as he didn't return from a PCL sprain in his knee until Week 11 after getting hurt in Week 4. In three games since his return, the 25-year-old former first-rounder has caught only five passes for 20 yards on nine targets. Overall, he's sporting a 25-347-0 line in seven games. It's not like he hasn't been on the field since his return, as he's played at least 75% of the snaps in all three games. Fantasy managers who have hung onto Pearsall will be hoping that the Niners will devise a plan to get him more involved when they come out of their Week 14 bye to face the Tennessee Titans on Sunday, Dec. 14. Better days could be ahead, but Pearsall is likely to continue to struggle for a high target share in an offense that has plenty of mouths to feed between Christian McCaffrey, George Kittle, and Jauan Jennings.
December 5, 2025 8:42 PM EST
Across 11 games this season, San Francisco 49ers wide receiver Jauan Jennings has recorded 41 catches for 458 yards and five touchdowns. As the 49ers hit their bye in Week 14, the 28-year-old is playing some of his best football. Across his last five games, Jennings has recorded 23 catches for 246 yards and four touchdowns on 33 targets. While San Francisco has other talented weapons on their offense, Jennings continues to play a highly consistent role in the team's passing game. He's seen at least six targets in six out of his last seven games played. Additionally, it appears 49ers wide receiver Brandon Aiyuk (knee) may not take the field at all in 2025 after San Francisco voided guarantees in his contract while he works his way back from a knee injury. Jennings looks like the WR1 in San Francisco and should remain a solid starting option for fantasy managers down the stretch of the season.
December 5, 2025 11:01 AM EST
Across 13 games this season, San Francisco 49ers running back Brian Robinson Jr. has recorded 72 carries for 328 yards and two touchdowns. While the 26-year-old has been productive when given the opportunity in his first season in San Francisco, his playing time upside is capped by the presence of superstar 49ers running back Christian McCaffrey. Robinson Jr. has yet to play more than 18 offensive snaps or log double-digit carries in any game this season. However, as the fantasy playoffs approach, Robinson Jr. could be worth rostering as a premium handcuff option. He's averaging a career-best 4.6 yards per rush attempt this season and would immediately profile as a starting fantasy running back if McCaffrey were to miss time due to injury. In leagues with 12 or more teams, Robinson Jr. could be worth rostering and stashing through San Francisco's Week 14 bye.
Brian Robinson Jr. player page.
December 2, 2025 9:50 PM EST
San Francisco 49ers wide receiver Ricky Pearsall was held to two catches for 14 yards on three targets in the team's 26-8 win over the Browns on Sunday. He now has five catches on nine targets for 20 yards since returning from his PCL injury in Week 11. High winds in Cleveland limited the effectiveness of the 49ers' passing attack, as quarterback Brock Purdy completed just 16 of his 29 pass attempts in the game. Jauan Jennings, George Kittle, and Christian McCaffrey accounted for half of the team's targets, leaving Pearsall once again the odd man out. The 49ers get a bye in Week 14, but Pearsall may be worth a stash. In Weeks 15 through 17, Pearsall will see favorable matchups against the Titans, Colts, and Bears, which could lead to a boon in production over the fantasy football playoffs.
December 2, 2025 5:14 PM EST
San Francisco 49ers wide receiver Jauan Jennings caught four of a team-high six targets for 39 yards and a touchdown in the team's 26-8 win over the Browns in Week 13. With Sunday's trip to the end zone, Jennings now has a touchdown reception in four of the 49ers' last five games. The 28-year-old has ranked first or second in team targets in every game going back to Week 7, though that has not equated to fantasy success. Jennings has had 45 receiving yards or fewer during that stretch, his recent spate of touchdowns salvaging otherwise mediocre production. The 49ers are on bye in Week 14, but Jennings will have a chance to step things up against some generous opponents in the fantasy football playoffs. In Weeks 15 through 17, San Francisco faces the Titans, Colts, and Bears, all of which rank in the top ten in points allowed to opposing wide receivers.
December 2, 2025 5:00 PM EST