These are the top fantasy football players of the San Francisco 49ers as ranked by Average Draft Position (ADP) in PPR-format mock drafts.
Data as of September 10, 2025.
| # | Name | Pos | Team | ADP | Bye |
|---|---|---|---|---|---|
| 1 | Christian McCaffrey | RB | SF | 1.08 | 14 |
| 2 | George Kittle | TE | SF | 4.08 | 14 |
| 3 | Brock Purdy | QB | SF | 6.09 | 14 |
| 4 | Ricky Pearsall | WR | SF | 7.06 | 14 |
| 5 | Jauan Jennings | WR | SF | 7.09 | 14 |
| 6 | San Francisco Defense | DEF | SF | 12.08 | 14 |
| 7 | Brandon Aiyuk | WR | SF | 12.11 | 14 |
Christian McCaffrey's current ADP is 1.08, which is the 8th pick of the 1st round, and 8th selection overall.
George Kittle's current ADP is 4.08, which is the 8th pick of the 4th round, and 43rd selection overall.
Brock Purdy's current ADP is 6.09, which is the 9th pick of the 6th round, and 69th selection overall.
Ricky Pearsall's current ADP is 7.06, which is the 6th pick of the 7th round, and 78th selection overall.
Jauan Jennings's current ADP is 7.09, which is the 9th pick of the 7th round, and 81st selection overall.
San Francisco Defense's current ADP is 12.08, which is the 8th pick of the 12th round, and 139th selection overall.
Brandon Aiyuk's current ADP is 12.11, which is the 11th pick of the 12th round, and 143rd selection overall.
| Week | Home/Away | Opponent |
|---|---|---|
| 1 | Away | Seattle Seahawks |
| 2 | Away | New Orleans Saints |
| 3 | Home | Arizona Cardinals |
| 4 | Home | Jacksonville Jaguars |
| 5 | Away | Los Angeles Rams |
| 6 | Away | Tampa Bay Buccaneers |
| 7 | Home | Atlanta Falcons |
| 8 | Away | Houston Texans |
| 9 | Away | New York Giants |
| 10 | Home | Los Angeles Rams |
| 11 | Away | Arizona Cardinals |
| 12 | Home | Carolina Panthers |
| 13 | Away | Cleveland Browns |
| 15 | Home | Tennessee Titans |
| 16 | Away | Indianapolis Colts |
| 17 | Home | Chicago Bears |
| 18 | Home | Seattle Seahawks |
San Francisco 49ers tight end Brayden Willis has been elevated from the practice squad ahead of the Week 17 matchup against the Chicago Bears. The elevation of Willis is not a good sign for fellow tight end George Kittle (ankle), who is questionable for this contest. The fact that Willis was brought up means Kittle is most likely going to miss this weekend's game. If Kittle sits, Jake Tonges figures to operate as the primary tight end in this offense. Tonges posted some decent performances earlier in the season when Kittle was sidelined. He could offer some streaming appeal to tight-end-needy fantasy managers, assuming Kittle is unable to play.
December 27, 2025 6:41 PM EST
San Francisco 49ers wide receiver Demarcus Robinson scored his first touchdown of the season in Week 16, but was only involved enough to see one other target and finished the game with two catches for 23 yards and the score. Since the 49ers' Week 14 bye, Robinson has slid back behind Kendrick Bourne on the depth chart, but saw a slight uptick in playing time last week with Ricky Pearsall (knee, ankle) sidelined due to injuries. Pearsall is questionable for Week 17, as is tight end George Kittle (ankle). Even if both players were to be declared inactive, Robinson would be a long shot to provide fantasy value. In 12 games with the 49ers, Robinson has averaged 2.3 targets per game and owns a 17-222-1 line despite the many injuries to key pass-catchers throughout the season. Robinson is too low of a priority in the 49ers' pecking order to warrant use in the final weekend of fantasy football.
Demarcus Robinson player page.
December 27, 2025 5:31 AM EST
San Francisco 49ers kicker Eddy Pineiro was six-for-six on extra point tries against the Colts in Week 16 and made two of his three field goal attempts. Pineiro was good from 25 and 38 yards out. His miss came on a 64-yard try at the end of the second quarter. It was his first missed field goal of 2025, making him 27-for-28 on the season. In Week 17, the 49ers host the Chicago Bears, with whom Pineiro made his NFL debut in 2019. The meeting between the two high-octane offenses carries one of the highest expected point totals of this week's slate, which could translate to Pineiro seeing a glut of opportunities to put points on the board. Pineiro, who ranks fifth among kickers in fantasy points per game, is a good option to plug into lineups for the final week of fantasy football.
December 27, 2025 5:19 AM EST
San Francisco 49ers tight end Jake Tonges could again be called on to fill the shoes of George Kittle (ankle), who is questionable for Week 17. With the 49ers taking on the Bears on Sunday Night Football, fantasy managers hoping to see Kittle take the field won't have many options should the tight end be declared inactive. Tonges, therefore, is one of the few potential substitutes left in play by kickoff. Tonges caught a touchdown pass from Brock Purdy in Week 1 and served as the 49ers' primary pass-catching tight end during Kittle's injured reserve stint, posting a 22-209-2 line from Weeks 2 to 6. Managers committed to Kittle would be wise to stash Tonges but should be advised to treat the latter as a touchdown-dependent option at tight end.
December 27, 2025 5:09 AM EST
San Francisco 49ers tight end George Kittle (ankle) missed each of the team's practices this week and is officially questionable for the team's clash with the Bears in Week 17. Kittle is expected to be a game-time decision, and with the teams being showcased on Sunday Night Football, fantasy managers will be left with few other options should he be declared inactive. The timing couldn't be worse for managers who rode Kittle, who has averaged 20 PPR points per game since Week 10, to the fantasy championship round. Managers hoping to see Kittle take the field need to take out an insurance policy. Backup Jake Tonges connected with quarterback Brock Purdy for a go-ahead touchdown in Week 1, and he logged a 22-209-2 line during Kittle's five-week stint on injured reserve earlier this season. On the other side of the ball, Colston Loveland is another low-owned option worthy of consideration.
December 27, 2025 4:54 AM EST
Copyright 2025 Fantasy Football Calculator | Image Source: Icon Sportswire. Not affiliated with the National Football League (NFL).
Stats powered by FantasyData.com.
