These are the top fantasy football players of the San Francisco 49ers as ranked by Average Draft Position (ADP) in PPR-format mock drafts.
Data as of November 20, 2025.
| # | Name | Pos | Team | ADP | Bye |
|---|
| Week | Home/Away | Opponent |
|---|---|---|
| 1 | Away | Seattle Seahawks |
| 2 | Away | New Orleans Saints |
| 3 | Home | Arizona Cardinals |
| 4 | Home | Jacksonville Jaguars |
| 5 | Away | Los Angeles Rams |
| 6 | Away | Tampa Bay Buccaneers |
| 7 | Home | Atlanta Falcons |
| 8 | Away | Houston Texans |
| 9 | Away | New York Giants |
| 10 | Home | Los Angeles Rams |
| 11 | Away | Arizona Cardinals |
| 12 | Home | Carolina Panthers |
| 13 | Away | Cleveland Browns |
| 15 | Home | Tennessee Titans |
| 16 | Away | Indianapolis Colts |
| 17 | Home | Chicago Bears |
| 18 | Home | Seattle Seahawks |
San Francisco 49ers quarterback Brock Purdy (toe) is a full-go at the first practice of the week on Thursday, according to head coach Kyle Shanahan. Purdy returned in Week 11 for the first time since aggravating a turf-toe injury in Week 4 and looked good, going 19-for-26 passing for 200 yards and three touchdowns in a blowout win over the Arizona Cardinals. The 25-year-old managed to avoid a setback with his toe and should be a full-go for the Monday night clash against the Carolina Panthers in Week 12. The Panthers' defense has been much-improved from a season ago and hasn't been a great matchup for opposing QBs in 2025, but Purdy should still be viewed as a midrange QB1 in fantasy football now that the Niners' offense is pretty much back to full strength for the first time all year. The one drawback to starting Purdy in fantasy lineups is that he might still be hesitant to run the ball because of his toe injury. He ran just once last week for a loss of seven yards.
November 20, 2025 5:12 PM EST
San Francisco 49ers quarterback Brock Purdy looked good in his return to play in Week 11 against the Arizona Cardinals, completing 19 of 26 passes for 200 yards and three touchdowns. Purdy produced his typical high-efficiency numbers after missing the last six games with a toe injury. The 25-year-old finished as QB6 for the week and looks primed for a strong rest of the season finish with San Francisco continuing to get healthier on offense. Wide receiver Ricky Pearsall also made his return from a multi-game absence in Week 11 against Arizona, and while he recorded just one reception for zero yards, the 2024 first-round pick looked excellent early in the season and developed a real rapport with Purdy. The Iowa State product is surrounded by a strong core of weapons and projects as a solid QB1 for Monday night against the Panthers in Week 12.
November 20, 2025 12:14 AM EST
The San Francisco 49ers signed free-agent kicker Matt Gay to their practice squad on Wednesday and released wide receiver Russell Gage Jr. from their practice squad in a corresponding move, according to Adam Schefter of ESPN. Eddy Pineiro (hamstring) suffered a Grade 1 hamstring strain in the Week 11 win over the Arizona Cardinals and is not expected to be available to kick this coming Monday night against the Carolina Panthers. Gay was just waived by the Washington Commanders on Monday after missing two kicks in a three-point loss to the Miami Dolphins on Sunday in Madrid. The 31-year-old veteran looks like he'll be the 49ers' short-term replacement at place kicker with Pineiro injured, but fantasy managers should be looking to stay away. The seven-year veteran has been inconsistent, making 13 of his 19 field-goal tries in 10 games, including going 4-for-9 from 50-plus yards out.
November 19, 2025 7:06 PM EST
San Francisco 49ers wide receiver Brandon Aiyuk (knee) is over a year removed from his injury and should be nearing a return based on the team's expectations coming into the season. However, he still hasn't had his 21-day practice window opened, and that won't happen this week, according to head coach Kyle Shanahan. While he's eligible to return at any point, the fact that he hasn't returned to practice at all yet indicates he's still multiple weeks away from making a significant fantasy impact. If you can stash him in an IR spot, he still could make a difference down the road, but for now, there are probably better options to have on your bench in most formats.
November 18, 2025 10:38 AM EST
The Washington Commanders released veteran kicker Matt Gay on Monday, according to Adam Schefter of ESPN. It's unclear who the Commanders plan on replacing Gay with, but they will likely bring in kickers over the next two weeks as they prepare to take on the Denver Broncos on Sunday Night Football in Week 13 following their Week 12 bye. The 31-year-old Gay was in the midst of a tough season with Washington, making a career-low 68.4% of his 19 field-goal attempts through 10 games this season. However, he was perfect on his 22 extra-point tries. Gay missed two field goals in Sunday's 16-13 overtime loss to the Miami Dolphins in Madrid, which was the last straw for the Commanders. Whoever the Commanders replace Gay with for their Week 13 game should be avoided in fantasy against a tough defense, with quarterback Jayden Daniels (elbow) likely out again.
November 17, 2025 5:47 PM EST
Copyright 2025 Fantasy Football Calculator | Image Source: Icon Sportswire. Not affiliated with the National Football League (NFL).
Stats powered by FantasyData.com.
