San Francisco
49ers
49ers Top Fantasy Players
These are the top fantasy football players of the San Francisco 49ers as ranked by Average Draft Position (ADP) in PPR-format mock drafts.
Data as of September 19, 2026.
| # | Name | Pos | Team | ADP | Bye |
|---|---|---|---|---|---|
| 1 | Mike Evans | WR | SF | 5.03 | 8 |
| 2 | Deebo Samuel Sr. | WR | SF | 9.11 | 8 |
| 3 | San Francisco Defense | DEF | SF | 13.09 | 8 |
| 4 | Kaelon Black | RB | SF | 13.10 | 8 |
Mike Evans
Mike Evans's current ADP is 5.03, which is the 3rd pick of the 5th round, and 51st selection overall.
Deebo Samuel Sr.
Deebo Samuel Sr.'s current ADP is 9.11, which is the 11th pick of the 9th round, and 106th selection overall.
San Francisco Defense
San Francisco Defense's current ADP is 13.09, which is the 9th pick of the 13th round, and 153rd selection overall.
Kaelon Black
Kaelon Black's current ADP is 13.10, which is the 10th pick of the 13th round, and 153rd selection overall.
San Francisco 49ers 2025 Schedule
| Week | Home/Away | Opponent |
|---|---|---|
| 1 | Away | Seattle Seahawks |
| 2 | Away | New Orleans Saints |
| 3 | Home | Arizona Cardinals |
| 4 | Home | Jacksonville Jaguars |
| 5 | Away | Los Angeles Rams |
| 6 | Away | Tampa Bay Buccaneers |
| 7 | Home | Atlanta Falcons |
| 8 | Away | Houston Texans |
| 9 | Away | New York Giants |
| 10 | Home | Los Angeles Rams |
| 11 | Away | Arizona Cardinals |
| 12 | Home | Carolina Panthers |
| 13 | Away | Cleveland Browns |
| 15 | Home | Tennessee Titans |
| 16 | Away | Indianapolis Colts |
| 17 | Home | Chicago Bears |
| 18 | Home | Seattle Seahawks |
San Francisco 49ers News
Eddy Piñeiro, Eddy Pineiro's Week 2 Potential Jeopardized By Illness
San Francisco 49ers kicker Eddy Pineiro (illness) went 2-for-3 on field goal attempts and converted all three of his three extra point opportunities in Week 1. Pineiro hit from 20 and 56 yards out and doinked a 52-yarder late in the fourth quarter when the game was already well in hand. Pineiro missed practice all week due to an illness and is listed as questionable for Week 2. According to Matt Maiocco of NBC Sports Bay Area, the 49ers will be adding a temporary replacement kicker in case Pineiro can't go on Sunday. If Pineiro is active, he should be in starting lineups as there will be plenty of opportunities for the 49ers to get on the board in a favorable matchup against the Miami Dolphins. As one of the last games on the slate for Week 2, fantasy managers may have to pivot to Pineiro's as-yet-unnamed replacement if he is inactive on Sunday.
September 18, 2026 11:01 PM EST
George Kittle, George Kittle Could See More Work In Week 2
San Francisco 49ers tight end George Kittle (Achilles) is off the injury report for Sunday's game against the Miami Dolphins. Kittle started the week with back-to-back limited practices but was a full participant on Friday. After tearing his Achilles in a wild card matchup last season, Kittle beat the typical recovery timeline and was on the field for 30 of the 49ers' 65 offensive snaps in last week's season opener, and caught two of his five targets for 12 yards. Another week stronger and with backup Jake Tonges (knee) on injured reserve, Kittle should see more involvement in what looks like a favorable matchup against Miami. Last week, Raiders tight end Michael Mayer pulled in six receptions, tying him for the team lead in their win over the Fins. Kittle may not be a ceiling play just yet, but he should be started as a potential TE1/2 in Week 2.
September 18, 2026 10:37 PM EST
Deebo Samuel Sr., Deebo Samuel Sr. In Line For Another Busy Week
San Francisco 49ers wide receiver Deebo Samuel Sr. was welcomed back to his former team with seven targets in Week 1. Samuel converted his chances into six catches for 48 yards and a touchdown in the 49ers' 27-7 win over the Rams. He also had one rushing attempt for 12 yards. De'Zhaun Stribling (ankle) will be inactive on Sunday as a consequence of a non-contact ankle injury suffered last week. His absence means Samuel will have less competition for targets in the 49ers' talented pass-catching corps. In Week 2, the 49ers are heavily favored against the Dolphins, meaning the offensive game plan will have increased focus on the ground game. Samuel could still make an impact there with rookie Kaelon Black (groin) listed as questionable. In his first stint with the Niners, Samuel averaged 3.1 carries per game from 2021 to 2024. He is a WR3/flex candidate for Week 2.
September 18, 2026 10:07 PM EST
Mike Evans, Mike Evans Has WR1 Potential In Week 2
San Francisco 49ers wide receiver Mike Evans had six receptions for 49 yards and one touchdown on seven targets in his debut with his new team in Week 1. The chemistry that Evans shared with Brock Purdy was immediately evident. On the 49ers' first drive alone, Purdy threw to Evans for three third-down conversions, and the veteran finished the game tied with Deebo Samuel Sr. for the team lead in receptions and targets. Already at the top of the 49ers' depth chart, Evans could see a few more targets with George Kittle (Achilles) still working back to full strength and De'Zhaun Stribling (ankle) out following his Week 1 non-contact ankle injury. This week, the 49ers are favored by almost two touchdowns against the Dolphins, which should mean less reliance on the passing game. Even if the potential blowout does take shape, Evans' likely involvement makes him a borderline WR1/2 and a must-start in Week 2.
September 18, 2026 9:25 PM EST
Kaelon Black, Kaelon Black Now A Risky Flex In Week 2
San Francisco 49ers running back Kaelon Black (groin) made a good first impression in his NFL debut last week. Black handled 14 carries for 65 yards and caught one pass for five receiving yards in the 49ers' Week 1 win over the Rams. San Francisco was in the driver's seat for much of the game, affording them the luxury of rotating Black into the backfield regularly in an effort to keep Christian McCaffrey fresh. Black was added to the injury report on Thursday due to groin tightness and is listed as questionable for Sunday's game against the Dolphins. With the 49ers heavily favored, Black started the week as a flex candidate in an expected blowout, but his updated status makes him a risky start. If Black is restricted, then fellow backup Jordan James might spell McCaffrey, with wide receiver Deebo Samuel Sr. potentially seeing some backfield work as well.
September 18, 2026 9:17 PM EST
