These are the top fantasy football players of the San Francisco 49ers as ranked by Average Draft Position (ADP) in PPR-format mock drafts.
Data as of September 10, 2025.
| # | Name | Pos | Team | ADP | Bye |
|---|---|---|---|---|---|
| 1 | Christian McCaffrey | RB | SF | 1.08 | 14 |
| 2 | George Kittle | TE | SF | 4.08 | 14 |
| 3 | Brock Purdy | QB | SF | 6.09 | 14 |
| 4 | Ricky Pearsall | WR | SF | 7.06 | 14 |
| 5 | Jauan Jennings | WR | SF | 7.09 | 14 |
| 6 | San Francisco Defense | DEF | SF | 12.08 | 14 |
| 7 | Brandon Aiyuk | WR | SF | 12.11 | 14 |
Christian McCaffrey's current ADP is 1.08, which is the 8th pick of the 1st round, and 8th selection overall.
George Kittle's current ADP is 4.08, which is the 8th pick of the 4th round, and 43rd selection overall.
Brock Purdy's current ADP is 6.09, which is the 9th pick of the 6th round, and 69th selection overall.
Ricky Pearsall's current ADP is 7.06, which is the 6th pick of the 7th round, and 78th selection overall.
Jauan Jennings's current ADP is 7.09, which is the 9th pick of the 7th round, and 81st selection overall.
San Francisco Defense's current ADP is 12.08, which is the 8th pick of the 12th round, and 139th selection overall.
Brandon Aiyuk's current ADP is 12.11, which is the 11th pick of the 12th round, and 143rd selection overall.
| Week | Home/Away | Opponent |
|---|---|---|
| 1 | Away | Seattle Seahawks |
| 2 | Away | New Orleans Saints |
| 3 | Home | Arizona Cardinals |
| 4 | Home | Jacksonville Jaguars |
| 5 | Away | Los Angeles Rams |
| 6 | Away | Tampa Bay Buccaneers |
| 7 | Home | Atlanta Falcons |
| 8 | Away | Houston Texans |
| 9 | Away | New York Giants |
| 10 | Home | Los Angeles Rams |
| 11 | Away | Arizona Cardinals |
| 12 | Home | Carolina Panthers |
| 13 | Away | Cleveland Browns |
| 15 | Home | Tennessee Titans |
| 16 | Away | Indianapolis Colts |
| 17 | Home | Chicago Bears |
| 18 | Home | Seattle Seahawks |
San Francisco 49ers tight end George Kittle was officially diagnosed with a torn Achilles following Sunday's Wild Card victory over the Philadelphia Eagles, head coach Kyle Shanahan confirmed. The superstar tight end suffered a non-contact injury while catching a pass during the second quarter. Video from the FOX broadcast appeared to show a pop in the back of Kittle's leg, and he was carted to the locker room in visible pain. The 49ers quickly ruled him out with an Achilles injury, and it was later confirmed to be a tear. The 32-year-old will now embark on a lengthy recovery process. Not only is he done for the 2025 playoffs, but he could miss the start of the 2026 regular season. If so, he'll likely drop several spots in the 2026 fantasy football draft tight end rankings. Jake Tonges should step up as the 49ers' top tight end for the rest of the playoffs before he becomes a restricted free agent in March. In the six games that Kittle missed during the regular season, Tonges totaled 29 catches, 269 yards, and three touchdowns. He caught just one pass for 14 yards in Kittle's absence this Sunday.
January 11, 2026 8:39 PM EST
San Francisco 49ers tight end George Kittle (Achilles) has been ruled out for the remainder of Sunday's playoff contest against the Philadelphia Eagles. The superstar tight end appeared to suffer a non-contact injury while catching a pass during the second quarter. Video from the FOX broadcast appeared to show a pop in the back of Kittle's leg, creating concern for a severe Achilles injury. He immediately reached for his lower leg, was in visible pain, and had to be carted to the locker room. The 32-year-old will now undergo additional testing as the 49ers work toward an official diagnosis. If the team's worst fears are confirmed, Kittle will likely miss the remainder of the 2025 NFL playoffs. Jake Tonges should earn more snaps in his absence. In the six games that Kittle missed during the regular season, Tonges totaled 29 catches, 269 yards, and three touchdowns. Tonges is a talented pass-catching tight end, but he doesn't come close to filling the enormous void left behind by Kittle's injury.
January 11, 2026 5:57 PM EST
San Francisco 49ers wide receiver Ricky Pearsall (knee, ankle) will remain sidelined for his team's Wild Card Weekend matchup against the Philadelphia Eagles. Pearsall re-aggravated an existing PCL injury in his knee in Week 17 and has not played since. The 25-year-old battled injuries throughout the regular season, recording 36 receptions for 528 yards on 53 targets across nine games played. Without him, San Francisco will likely turn to veteran wide receivers Demarcus Robinson and Kendrick Bourne for pass-catching snaps alongside WR1 Jauan Jennings. Robinson was the more heavily utilized wideout of the two in Week 18, playing 88% of the 49ers' offensive snaps and hauling in three receptions for 24 yards on four targets.
January 11, 2026 3:23 PM EST
Across 11 games played during the 2025 regular season, San Francisco 49ers tight end George Kittle recorded 57 receptions for 628 yards and seven touchdowns on 69 targets. After an injury-marred start to the year, Kittle closed the season strong. Across seven games from Week 10 onwards, Kittle recorded at least 13.8 PPR fantasy points five times. In the Wild Card round, Kittle and the 49ers will face a tough test against the Philadelphia Eagles. The Eagles' defense finished the regular season ranked fifth in yards per pass attempt allowed (6.4) and allowed the fewest passing touchdowns (14) of any team in the NFL. However, Kittle has proven throughout his nine-year NFL career that he's capable of producing against any opponent. He profiles as the number one tight end option for fantasy managers in playoff leagues in the Wild Card round.
January 11, 2026 3:00 PM EST
San Francisco 49ers quarterback Brock Purdy had a performance to forget in his team's regular-season finale, throwing for 127 yards and an interception in a loss to the Seattle Seahawks. However, the 26-year-old was playing excellent football before running into Seattle, throwing for 893 yards and 11 touchdowns across a three-game stretch between Week 15 and Week 17. In the Wild Card Round, San Francisco will take on a tough matchup in the Philadelphia Eagles. The Eagles' defense finished the regular season ranked fifth in yards per pass attempt allowed (6.4) and allowed the fewest passing touchdowns (14) of any team in the NFL. On the plus side for Purdy, 49ers superstar left tackle Trent Williams (hamstring) is expected to play against the Eagles after missing Week 18 with a hamstring injury. All in all, RotoBaller ranks Purdy as the QB7 for fantasy managers in playoff leagues heading into Wild Card Weekend.
January 11, 2026 2:50 PM EST
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