These are the top fantasy football players of the San Francisco 49ers as ranked by Average Draft Position (ADP) in PPR-format mock drafts.
Data as of September 10, 2025.
| # | Name | Pos | Team | ADP | Bye |
|---|---|---|---|---|---|
| 1 | Christian McCaffrey | RB | SF | 1.08 | 14 |
| 2 | George Kittle | TE | SF | 4.08 | 14 |
| 3 | Brock Purdy | QB | SF | 6.09 | 14 |
| 4 | Ricky Pearsall | WR | SF | 7.06 | 14 |
| 5 | Jauan Jennings | WR | SF | 7.09 | 14 |
| 6 | San Francisco Defense | DEF | SF | 12.08 | 14 |
| 7 | Brandon Aiyuk | WR | SF | 12.11 | 14 |
Christian McCaffrey's current ADP is 1.08, which is the 8th pick of the 1st round, and 8th selection overall.
George Kittle's current ADP is 4.08, which is the 8th pick of the 4th round, and 43rd selection overall.
Brock Purdy's current ADP is 6.09, which is the 9th pick of the 6th round, and 69th selection overall.
Ricky Pearsall's current ADP is 7.06, which is the 6th pick of the 7th round, and 78th selection overall.
Jauan Jennings's current ADP is 7.09, which is the 9th pick of the 7th round, and 81st selection overall.
San Francisco Defense's current ADP is 12.08, which is the 8th pick of the 12th round, and 139th selection overall.
Brandon Aiyuk's current ADP is 12.11, which is the 11th pick of the 12th round, and 143rd selection overall.
| Week | Home/Away | Opponent |
|---|---|---|
| 1 | Away | Seattle Seahawks |
| 2 | Away | New Orleans Saints |
| 3 | Home | Arizona Cardinals |
| 4 | Home | Jacksonville Jaguars |
| 5 | Away | Los Angeles Rams |
| 6 | Away | Tampa Bay Buccaneers |
| 7 | Home | Atlanta Falcons |
| 8 | Away | Houston Texans |
| 9 | Away | New York Giants |
| 10 | Home | Los Angeles Rams |
| 11 | Away | Arizona Cardinals |
| 12 | Home | Carolina Panthers |
| 13 | Away | Cleveland Browns |
| 15 | Home | Tennessee Titans |
| 16 | Away | Indianapolis Colts |
| 17 | Home | Chicago Bears |
| 18 | Home | Seattle Seahawks |
San Francisco 49ers tight end Jake Tonges will be a legitimate top-five TE option for fantasy managers in playoff leagues for the Divisional Round on Saturday night against the Seattle Seahawks, following George Kittle's torn Achilles tendon in the Wild-Card win over the Philadelphia Eagles. The last time Kittle sat out with an injury on Dec. 28 in the win over the Chicago Bears, Tonges had seven catches on nine targets for 60 yards and a touchdown. He also had seven grabs on a season-high 11 targets for 41 yards and a score back in the Oct. 2 overtime win over the Los Angeles Rams when Kittle was out due to injury. The Niners will be facing a stout Seattle defense that held them to just three points in the Week 18 regular-season finale, but their D did allow the 11th-most half-PPR fantasy points per game to TEs during the regular season.
January 16, 2026 9:09 PM EST
San Francisco 49ers quarterback Brock Purdy was far from perfect in his team's Wild Card Weekend win over the Philadelphia Eagles. The 26-year-old completed 18 of 31 pass attempts for 262 yards and two touchdowns, but he also threw two interceptions. Dating back to the regular season, Purdy has now thrown an interception in four consecutive games. In the Divisional Round, San Francisco will travel to Seattle to take on the Seahawks. Seattle completely shut Purdy down in the regular season finale for both teams, holding Purdy to 19 of 27 passing for 127 yards, zero touchdowns, and a pick. The Seahawks defense was dominant throughout the regular season, finishing first in the NFL in yards per pass attempt allowed (6.0) and tied for seventh in sacks (47). Making matters worse for Purdy, he'll be without one of his top receiving weapons in tight end George Kittle (Achilles), who suffered a season-ending torn Achilles tendon in the Wild Card Round. Given the matchup and San Francisco's depleted pass-catching corps, Purdy profiles as a quarterback for fantasy managers to avoid in the Divisional Round.
January 16, 2026 3:24 PM EST
San Francisco 49ers tight end George Kittle (Achilles) underwent successful surgery to fix his torn right Achilles tendon on Wednesday, according to head coach Kyle Shanahan. Kittle was placed on Injured Reserve on Wednesday and will miss the rest of the playoffs. Because his injury occurred so late in the year, too, the 32-year-old veteran almost certainly won't be ready for the start of the 2026 campaign this fall. In fact, he could end up missing the majority of next regular season after tearing his Achilles in the Wild-Card win over the Philadelphia Eagles last Sunday. Going into this Saturday's NFC Divisional contest against the Seattle Seahawks, Jake Tonges will take over as the Niners' top pass-catching tight end. Kittle, a seven-time Pro Bowler, still has high-end TE1 upside when healthy, but durability concerns will drastically affect his 2026 fantasy value.
January 15, 2026 7:07 PM EST
San Francisco 49ers head coach Kyle Shanahan said that wide receiver Ricky Pearsall (knee, ankle) will be questionable to play in the Divisional Round of the playoffs on Saturday evening on the road against the division-rival Seattle Seahawks, according to Matt Barrows of The Athletic. Pearsall missed a good chunk of his second NFL season due to a sprained PCL in his right knee, and he's also missed three of the last four games, including last week's Wild-Card win over the Philadelphia Eagles, after aggravating his knee. San Fran could really use the 25-year-old former first-rounder back against Seattle after losing tight end George Kittle to a torn Achilles tendon last Sunday. Pearsall was limited in practice all week and is optimistic he'll be available on Saturday night. He did go over 100 receiving yards in two of his last three games, but Pearsall has been very hit or miss and injury-prone, making him extremely volatile as a fantasy option in playoff leagues in a bad matchup if he's active.
January 15, 2026 6:55 PM EST
San Francisco 49ers wide receiver Ricky Pearsall (knee, ankle) is "optimistic" that he will return in the Divisional Round of the playoffs this Saturday night against the division-rival Seattle Seahawks and plans to be at full speed in practice on Wednesday, according to David Lombardi of The San Francisco Standard. Pearsall practiced in a limited fashion on Tuesday for the first time since Dec. 31 due to an aggravation of a PCL sprain in his right knee. The 25-year-old former first-rounder is also battling an ankle injury. Injuries continued to be an issue for Pearsall in 2025 -- he played in just nine games -- but he appears to be trending in the right direction to be active against Seattle. That would be a big boost to a Niners offense that just lost star tight end George Kittle to a torn Achilles tendon. It would also be bad news for the fantasy upside of both receivers Jauan Jennings and Demarcus Robinson.
January 14, 2026 3:24 PM EST
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