These are the top fantasy football players of the San Francisco 49ers as ranked by Average Draft Position (ADP) in PPR-format mock drafts.
Data as of September 10, 2025.
| # | Name | Pos | Team | ADP | Bye |
|---|---|---|---|---|---|
| 1 | Christian McCaffrey | RB | SF | 1.08 | 14 |
| 2 | George Kittle | TE | SF | 4.08 | 14 |
| 3 | Brock Purdy | QB | SF | 6.09 | 14 |
| 4 | Ricky Pearsall | WR | SF | 7.06 | 14 |
| 5 | Jauan Jennings | WR | SF | 7.09 | 14 |
| 6 | San Francisco Defense | DEF | SF | 12.08 | 14 |
| 7 | Brandon Aiyuk | WR | SF | 12.11 | 14 |
Christian McCaffrey's current ADP is 1.08, which is the 8th pick of the 1st round, and 8th selection overall.
George Kittle's current ADP is 4.08, which is the 8th pick of the 4th round, and 43rd selection overall.
Brock Purdy's current ADP is 6.09, which is the 9th pick of the 6th round, and 69th selection overall.
Ricky Pearsall's current ADP is 7.06, which is the 6th pick of the 7th round, and 78th selection overall.
Jauan Jennings's current ADP is 7.09, which is the 9th pick of the 7th round, and 81st selection overall.
San Francisco Defense's current ADP is 12.08, which is the 8th pick of the 12th round, and 139th selection overall.
Brandon Aiyuk's current ADP is 12.11, which is the 11th pick of the 12th round, and 143rd selection overall.
| Week | Home/Away | Opponent |
|---|---|---|
| 1 | Away | Seattle Seahawks |
| 2 | Away | New Orleans Saints |
| 3 | Home | Arizona Cardinals |
| 4 | Home | Jacksonville Jaguars |
| 5 | Away | Los Angeles Rams |
| 6 | Away | Tampa Bay Buccaneers |
| 7 | Home | Atlanta Falcons |
| 8 | Away | Houston Texans |
| 9 | Away | New York Giants |
| 10 | Home | Los Angeles Rams |
| 11 | Away | Arizona Cardinals |
| 12 | Home | Carolina Panthers |
| 13 | Away | Cleveland Browns |
| 15 | Home | Tennessee Titans |
| 16 | Away | Indianapolis Colts |
| 17 | Home | Chicago Bears |
| 18 | Home | Seattle Seahawks |
San Francisco 49ers running back Christian McCaffrey (shoulder) exited with a stinger during the third quarter of Saturday's Divisional Round contest against the Seattle Seahawks. He was briefly listed as questionable to return, but he checked back into the game midway through the third quarter. The superstar running back took multiple hits throughout the first 30-plus minutes of game action, and he was seeing testing his injury on the sideline. At the time of his initial departure, McCaffrey had totaled nine carries, 29 rushing yards, five catches, and 39 receiving yards. Bad injury news has plagued the 49ers left and right. In addition to various defensive injuries throughout the regular season, San Francisco lost George Kittle (Achilles) last week, and Jake Tonges (foot) is currently listed as questionable to return against Seattle. For the time being, McCaffrey will try to play through his injury with the 49ers' season on the line. However, we wouldn't be surprised to see No. 2 running back Brian Robinson Jr. earn more snaps while McCaffrey manages his injury.
Christian McCaffrey player page.
January 17, 2026 10:30 PM EST
San Francisco 49ers tight end Jake Tonges (foot) exited during the third quarter of Saturday's Divisional Round contest against the Seattle Seahawks. He is officially listed as questionable to return. Tonges suffered the injury following an incomplete pass, and he was seen trying to test his foot on the sideline. At the time of his departure, he had caught five of six targets for 59 yards. The 26-year-old earned the start at tight end after George Kittle (Achilles) was ruled out for the remainder of the playoffs. Throughout the seven games that Kittle has missed between the regular season and playoffs, Tonges has amassed 34 catches, 328 yards, and three touchdowns. It goes without saying that losing both Kittle and Tonges is terrible news for the Niners, who are trying to come back from a three-possession deficit in Seattle. Luke Farrell should take over as San Francisco's primary tight end for the time being.
January 17, 2026 10:23 PM EST
San Francisco 49ers wide receiver Ricky Pearsall (knee) is officially active for Saturday's Divisional Round contest against the Seattle Seahawks. He had been listed as questionable after practicing in a limited capacity. Pearsall returns to action following a two-game absence. Injuries bothered him throughout most of the regular season, limiting him to just 36 catches, 528 yards, and zero touchdowns through nine games. His return comes at a perfect time for the Niners, who were in need of pass-catching reinforcements after losing George Kittle (Achilles) for the rest of the playoffs. Pearsall will step up as the No. 2 receiver alongside Jauan Jennings against Seattle. The last time he faced the Seahawks, back in Week 1, Pearsall caught four passes for 108 yards.
January 17, 2026 6:53 PM EST
San Francisco 49ers tight end Jake Tonges will be a legitimate top-five TE option for fantasy managers in playoff leagues for the Divisional Round on Saturday night against the Seattle Seahawks, following George Kittle's torn Achilles tendon in the Wild-Card win over the Philadelphia Eagles. The last time Kittle sat out with an injury on Dec. 28 in the win over the Chicago Bears, Tonges had seven catches on nine targets for 60 yards and a touchdown. He also had seven grabs on a season-high 11 targets for 41 yards and a score back in the Oct. 2 overtime win over the Los Angeles Rams when Kittle was out due to injury. The Niners will be facing a stout Seattle defense that held them to just three points in the Week 18 regular-season finale, but their D did allow the 11th-most half-PPR fantasy points per game to TEs during the regular season.
January 16, 2026 9:09 PM EST
San Francisco 49ers quarterback Brock Purdy was far from perfect in his team's Wild Card Weekend win over the Philadelphia Eagles. The 26-year-old completed 18 of 31 pass attempts for 262 yards and two touchdowns, but he also threw two interceptions. Dating back to the regular season, Purdy has now thrown an interception in four consecutive games. In the Divisional Round, San Francisco will travel to Seattle to take on the Seahawks. Seattle completely shut Purdy down in the regular season finale for both teams, holding Purdy to 19 of 27 passing for 127 yards, zero touchdowns, and a pick. The Seahawks defense was dominant throughout the regular season, finishing first in the NFL in yards per pass attempt allowed (6.0) and tied for seventh in sacks (47). Making matters worse for Purdy, he'll be without one of his top receiving weapons in tight end George Kittle (Achilles), who suffered a season-ending torn Achilles tendon in the Wild Card Round. Given the matchup and San Francisco's depleted pass-catching corps, Purdy profiles as a quarterback for fantasy managers to avoid in the Divisional Round.
January 16, 2026 3:24 PM EST