These are the top fantasy football players of the San Francisco 49ers as ranked by Average Draft Position (ADP) in PPR-format mock drafts.
Data as of September 10, 2025.
| # | Name | Pos | Team | ADP | Bye |
|---|---|---|---|---|---|
| 1 | Christian McCaffrey | RB | SF | 1.08 | 14 |
| 2 | George Kittle | TE | SF | 4.08 | 14 |
| 3 | Brock Purdy | QB | SF | 6.09 | 14 |
| 4 | Ricky Pearsall | WR | SF | 7.06 | 14 |
| 5 | Jauan Jennings | WR | SF | 7.09 | 14 |
| 6 | San Francisco Defense | DEF | SF | 12.08 | 14 |
| 7 | Brandon Aiyuk | WR | SF | 12.11 | 14 |
Christian McCaffrey's current ADP is 1.08, which is the 8th pick of the 1st round, and 8th selection overall.
George Kittle's current ADP is 4.08, which is the 8th pick of the 4th round, and 43rd selection overall.
Brock Purdy's current ADP is 6.09, which is the 9th pick of the 6th round, and 69th selection overall.
Ricky Pearsall's current ADP is 7.06, which is the 6th pick of the 7th round, and 78th selection overall.
Jauan Jennings's current ADP is 7.09, which is the 9th pick of the 7th round, and 81st selection overall.
San Francisco Defense's current ADP is 12.08, which is the 8th pick of the 12th round, and 139th selection overall.
Brandon Aiyuk's current ADP is 12.11, which is the 11th pick of the 12th round, and 143rd selection overall.
| Week | Home/Away | Opponent |
|---|---|---|
| 1 | Away | Seattle Seahawks |
| 2 | Away | New Orleans Saints |
| 3 | Home | Arizona Cardinals |
| 4 | Home | Jacksonville Jaguars |
| 5 | Away | Los Angeles Rams |
| 6 | Away | Tampa Bay Buccaneers |
| 7 | Home | Atlanta Falcons |
| 8 | Away | Houston Texans |
| 9 | Away | New York Giants |
| 10 | Home | Los Angeles Rams |
| 11 | Away | Arizona Cardinals |
| 12 | Home | Carolina Panthers |
| 13 | Away | Cleveland Browns |
| 15 | Home | Tennessee Titans |
| 16 | Away | Indianapolis Colts |
| 17 | Home | Chicago Bears |
| 18 | Home | Seattle Seahawks |
San Francisco 49ers wide receiver Ricky Pearsall (knee, ankle) was a limited participant during Wednesday's practice session. Pearsall sat out during Monday's win over the Indianapolis Colts due to nagging knee and ankle issues. He's clearly still dealing with the issues, but at least he was able to practice in a limited capacity. Fantasy managers will need to monitor his status over the next few days ahead of the Week 17 matchup against the Chicago Bears on Sunday night. Another absence from Pearsall would mean increased roles for Jauan Jennings, Kendrick Bourne, and Demarcus Robinson. Jennings is the most consistent contributor out of the three wideouts right now for the Niners offense. Even if Pearsall plays in Week 17, it will be hard to recommend him for a flex spot in fantasy football lineups with championships on the line.
December 24, 2025 9:35 PM EST
San Francisco 49ers tight end George Kittle (ankle) "has a chance" to play on Sunday night against the Chicago Bears in Week 17, according to head coach Kyle Shanahan. Kittle is not taking part in Wednesday's practice, but the team will see how he does in the next few days. The 32-year-old Pro Bowl tight end suffered an ankle sprain in the second half of Monday night's blowout win over the Indianapolis Colts and didn't return. He might not need to practice at all this week to play, but it could be a tough decision for fantasy managers to make on Kittle if he's a true game-time decision with this weekend's contest coming on Sunday night. Kittle is a no-doubt, must-start TE1 in fantasy when he's healthy. If the Niners play it safe and keep him out against the Bears, Jake Tonges would enter the TE2 streaming picture in deeper leagues.
December 24, 2025 4:31 PM EST
San Francisco 49ers tight end Jake Tonges has an opportunity to produce in Week 17 as the 49ers face the Chicago Bears. Tonges has hauled in 27 of 37 targets for 233 yards and four touchdowns, with most of his production coming early in the season. George Kittle (ankle) injured his ankle in the 48-27 victory over the Indianapolis Colts, which could open the door for Tonges to have a viable role in this offense. In the six games that Kittle missed or left early in the season, Tonges had 25 receptions for 224 yards and three touchdowns, averaging 10.9 PPR points per game, which ranked ninth among tight ends during that span. Kittle's injury will determine whether the third-year tight end will have any fantasy value in Week 17, so fantasy managers should keep a close eye on the 49ers' practice reports this week.
December 24, 2025 11:02 AM EST
San Francisco 49ers tight end George Kittle (ankle) was forced to make an early exit from Monday's win over the Indianapolis Colts. The good news is that Kittle appears to have avoided any serious issues. According to Jeremy Fowler of ESPN, Kittle suffered a mid-to-low ankle sprain during Monday's blowout victory at Indy. His status for the Week 17 matchup against the Chicago Bears is up in the air right now. The 49ers will monitor Kittle during practice throughout the week before making a final decision. Fantasy managers will need to check back throughout the week for more updates on his status. Jake Tonges would be in line for increased playing time if Kittle is forced to miss any action, and he'd be in play as a TE2 streamer in deeper leagues if Kittle is unable to face Chicago on Sunday night.
December 23, 2025 7:09 PM EST
San Francisco 49ers wide receiver Demarcus Robinson caught his first touchdown pass of the season in the team's 48-27 win over the Colts on Monday night. Robinson finished the game with two catches for 22 yards and the score on two targets. Outside of the trip to the end zone, Robinson did not benefit from Ricky Pearsall's (knee, ankle) absence from the game. Instead, Robinson appears to have slipped back behind Kendrick Bourne on the depth chart, seeing a 44% snap share to Bourne's 70% share. Given his lack of involvement in the offense all season, fantasy football managers shouldn't read too much into Robinson's touchdown on Monday. It is too early to know Pearsall's status for Week 17, but even if he is held out, Robinson should not be relied on in the fantasy football championship round.
Demarcus Robinson player page.
December 23, 2025 6:26 PM EST
Copyright 2025 Fantasy Football Calculator | Image Source: Icon Sportswire. Not affiliated with the National Football League (NFL).
Stats powered by FantasyData.com.
