These are the top fantasy football players of the San Francisco 49ers as ranked by Average Draft Position (ADP) in PPR-format mock drafts.
Data as of September 10, 2025.
| # | Name | Pos | Team | ADP | Bye |
|---|---|---|---|---|---|
| 1 | Christian McCaffrey | RB | SF | 1.08 | 14 |
| 2 | George Kittle | TE | SF | 4.08 | 14 |
| 3 | Brock Purdy | QB | SF | 6.09 | 14 |
| 4 | Ricky Pearsall | WR | SF | 7.06 | 14 |
| 5 | Jauan Jennings | WR | SF | 7.09 | 14 |
| 6 | San Francisco Defense | DEF | SF | 12.08 | 14 |
| 7 | Brandon Aiyuk | WR | SF | 12.11 | 14 |
Christian McCaffrey's current ADP is 1.08, which is the 8th pick of the 1st round, and 8th selection overall.
George Kittle's current ADP is 4.08, which is the 8th pick of the 4th round, and 43rd selection overall.
Brock Purdy's current ADP is 6.09, which is the 9th pick of the 6th round, and 69th selection overall.
Ricky Pearsall's current ADP is 7.06, which is the 6th pick of the 7th round, and 78th selection overall.
Jauan Jennings's current ADP is 7.09, which is the 9th pick of the 7th round, and 81st selection overall.
San Francisco Defense's current ADP is 12.08, which is the 8th pick of the 12th round, and 139th selection overall.
Brandon Aiyuk's current ADP is 12.11, which is the 11th pick of the 12th round, and 143rd selection overall.
| Week | Home/Away | Opponent |
|---|---|---|
| 1 | Away | Seattle Seahawks |
| 2 | Away | New Orleans Saints |
| 3 | Home | Arizona Cardinals |
| 4 | Home | Jacksonville Jaguars |
| 5 | Away | Los Angeles Rams |
| 6 | Away | Tampa Bay Buccaneers |
| 7 | Home | Atlanta Falcons |
| 8 | Away | Houston Texans |
| 9 | Away | New York Giants |
| 10 | Home | Los Angeles Rams |
| 11 | Away | Arizona Cardinals |
| 12 | Home | Carolina Panthers |
| 13 | Away | Cleveland Browns |
| 15 | Home | Tennessee Titans |
| 16 | Away | Indianapolis Colts |
| 17 | Home | Chicago Bears |
| 18 | Home | Seattle Seahawks |
San Francisco 49ers wide receiver Ricky Pearsall (knee, ankle) will be listed as a limited participant on the team's estimated injury report on Tuesday, according to Nick Wagoner of ESPN. Pearsall is back at practice for the first time since Dec. 31 after aggravating a PCL sprain in his right knee. The 25-year-old has a shot to return for the Divisional Round of the playoffs against the Seattle Seahawks, but Pearsall should still be considered very questionable for the weekend. The Niners really could use the former first-rounder back after they lost tight end George Kittle to a torn Achilles tendon last weekend. If Pearsall is limited or misses yet another game due to knee and ankle injuries, Demarcus Robinson could be in line for heavy targets for the second straight week. Robinson broke out for six catches, 111 yards, and a touchdown on a season-high seven targets in the Wild-Card win over the Eagles with Pearsall out.
January 13, 2026 7:09 PM EST
San Francisco 49ers head coach Kyle Shanahan announced on Tuesday that star tight end George Kittle (Achilles) will have surgery to fix his torn Achilles tendon on Wednesday. Kittle tore his right Achilles tendon in Sunday's win over the Philadelphia Eagles in the Wild-Card round, so the team will be without him for the rest of the postseason and most likely the start of next season. He also missed time with injuries in 2025, but when healthy, he was a top-five fantasy TE in terms of half-PPR points per game (12.1) with 57 catches on 69 targets for 628 yards and seven touchdowns in 11 regular-season contests. The rest of the way, Jake Tonges will step in as San Fran's top pass-catching TE. In the win over the Chicago Bears on Dec. 28 without Kittle available, Tonges had seven catches for 60 yards and his fifth touchdown of the year.
January 13, 2026 7:03 PM EST
San Francisco 49ers tight end George Kittle was officially diagnosed with a torn Achilles following Sunday's Wild Card victory over the Philadelphia Eagles, head coach Kyle Shanahan confirmed. The superstar tight end suffered a non-contact injury while catching a pass during the second quarter. Video from the FOX broadcast appeared to show a pop in the back of Kittle's leg, and he was carted to the locker room in visible pain. The 49ers quickly ruled him out with an Achilles injury, and it was later confirmed to be a tear. The 32-year-old will now embark on a lengthy recovery process. Not only is he done for the 2025 playoffs, but he could miss the start of the 2026 regular season. If so, he'll likely drop several spots in the 2026 fantasy football draft tight end rankings. Jake Tonges should step up as the 49ers' top tight end for the rest of the playoffs before he becomes a restricted free agent in March. In the six games that Kittle missed during the regular season, Tonges totaled 29 catches, 269 yards, and three touchdowns. He caught just one pass for 14 yards in Kittle's absence this Sunday.
January 11, 2026 8:39 PM EST
San Francisco 49ers tight end George Kittle (Achilles) has been ruled out for the remainder of Sunday's playoff contest against the Philadelphia Eagles. The superstar tight end appeared to suffer a non-contact injury while catching a pass during the second quarter. Video from the FOX broadcast appeared to show a pop in the back of Kittle's leg, creating concern for a severe Achilles injury. He immediately reached for his lower leg, was in visible pain, and had to be carted to the locker room. The 32-year-old will now undergo additional testing as the 49ers work toward an official diagnosis. If the team's worst fears are confirmed, Kittle will likely miss the remainder of the 2025 NFL playoffs. Jake Tonges should earn more snaps in his absence. In the six games that Kittle missed during the regular season, Tonges totaled 29 catches, 269 yards, and three touchdowns. Tonges is a talented pass-catching tight end, but he doesn't come close to filling the enormous void left behind by Kittle's injury.
January 11, 2026 5:57 PM EST
San Francisco 49ers wide receiver Ricky Pearsall (knee, ankle) will remain sidelined for his team's Wild Card Weekend matchup against the Philadelphia Eagles. Pearsall re-aggravated an existing PCL injury in his knee in Week 17 and has not played since. The 25-year-old battled injuries throughout the regular season, recording 36 receptions for 528 yards on 53 targets across nine games played. Without him, San Francisco will likely turn to veteran wide receivers Demarcus Robinson and Kendrick Bourne for pass-catching snaps alongside WR1 Jauan Jennings. Robinson was the more heavily utilized wideout of the two in Week 18, playing 88% of the 49ers' offensive snaps and hauling in three receptions for 24 yards on four targets.
January 11, 2026 3:23 PM EST
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