These are the top fantasy football players of the San Francisco 49ers as ranked by Average Draft Position (ADP) in PPR-format mock drafts.
Data as of February 22, 2025.
| # | Name | Pos | Team | ADP | Bye |
|---|
| Week | Home/Away | Opponent |
|---|---|---|
| 1 | Home | New York Jets |
| 2 | Away | Minnesota Vikings |
| 3 | Away | Los Angeles Rams |
| 4 | Home | New England Patriots |
| 5 | Home | Arizona Cardinals |
| 6 | Away | Seattle Seahawks |
| 7 | Home | Kansas City Chiefs |
| 8 | Home | Dallas Cowboys |
| 10 | Away | Tampa Bay Buccaneers |
| 11 | Home | Seattle Seahawks |
| 12 | Away | Green Bay Packers |
| 13 | Away | Buffalo Bills |
| 14 | Home | Chicago Bears |
| 15 | Home | Los Angeles Rams |
| 16 | Away | Miami Dolphins |
| 17 | Home | Detroit Lions |
| 18 | Away | Arizona Cardinals |
San Francisco Chronicle's Eric Branch writes that the San Francisco 49ers and star tight end George Kittle have been in talks about a contract extension early this offseason. The 31-year-old is heading into the final year of his current deal in 2025 after a strong 2024 campaign in which he caught 78 passes on 94 targets for 1,106 receiving yards and eight touchdowns in 15 starts. The production was all the more impressive after he revealed that he played through cracked ribs for much of the season, and he also missed two games with a hamstring ailment. Kittle's 1,106 receiving yards and eight touchdowns were both the second-best marks of his career. He was the TE1 overall in fantasy, with only Brock Bowers and Trey McBride besting him in total yardage. Regardless of whether he gets a contract extension from the Niners (he likely will), Kittle will be a top-five fantasy TE in drafts this fall.
February 21, 2025 9:33 PM EST
San Francisco 49ers wide receiver Brandon Aiyuk (knee) could be ready for Week 1 of the 2025 NFL season, though his status is uncertain for now. The 26-year-old suffered a torn ACL and MCL in October of last season, so the recovery timeline makes it realistic for him to be ready for the start of the new campaign. Following a 1,400-yard receiving season in 2023, the 49ers signed Aiyuk to a four-year, $120 million contract. Unfortunately, he could only produce 25 receptions for 374 yards and no touchdowns in seven games in 2024. That said, Aiyuk could be a value pick in fantasy football coming off the injury, especially since Deebo Samuel appears to finally be on the way out of San Francisco via trade at some point this offseason.
February 11, 2025 2:41 PM EST
San Francisco 49ers owner Jed York reaffirmed the team's commitment to keeping quarterback Brock Purdy around long-term. "I know we want Brock to be here for a long time and we'll do everything we can to make that work," York said Monday. After selecting Purdy with the final pick of the 2022 draft, he has led them to two playoff appearances, including a Super Bowl, in his three years in the league. Now eligible for a new contract, the 49ers have remained committed to giving the 25-year-old a big contract he deserves. Both sides have been in talks on an extension, with Purdy saying last month that he wanted something "done quick" so that negotiations didn't extend into the offseason program. Even though Purdy's numbers dipped in 2024, he could land a deal worth more than $55 million per season. Purdy had career-lows in completion percentage (65.9), passer rating (96.1) and TD-to-interception ratio (20-12).
February 11, 2025 2:17 PM EST
The San Francisco 49ers gave wide receiver Deebo Samuel Sr. permission to seek a trade this offseason. Samuel is under contract for one more season, and his deal includes a $15 million option bonus. Along with his drop in production in 2024, it could suppress Samuel's trade market, but NBC Sports Bay Area's Matt Maiocco lists the Buffalo Bills, Los Angeles Chargers, Washington Commanders, Pittsburgh Steelers and Houston Texans as a few teams that could be interested in acquiring Samuel from the Niners. The 29-year-old former second-rounder had career-lows of 3.4 catches and 44.7 receiving yards per game in 15 contests in 2024, with his per-rush average also dropping to 3.2 yards. Although Samuel is much more of an injury risk with declining production, he does have 42 total TDs in six NFL seasons and will draw interest from receiver-needy teams as a trade target.
February 10, 2025 6:11 PM EST
The Athletic's Dianna Russini writes that the San Francisco 49ers will get a long-term contract extension done with quarterback Brock Purdy. The Niners won't drag their feet on this one -- they want a deal done soon and have already started conversations with Purdy's representatives. Even after a disappointing 2024 season, the team has not wavered on Purdy being their franchise signal-caller. "Everybody out there, if you have any questions about Brock Purdy, I'm here to tell you I'm not biased, I know ball he's the guy," linebacker Fred Warner said. The 25-year-old Purdy suffered a right-elbow injury at the tail end of the regular season but should be just fine this offseason and for Week 1 in 2025. He took a step back after his 2023 breakout, but injuries to key offensive weapons didn't help. Purdy should be a rebound candidate and should be considered a low-end QB1 in fantasy, at worst, in 2025.
February 9, 2025 1:22 PM EST
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