These are the top fantasy football players of the San Francisco 49ers as ranked by Average Draft Position (ADP) in PPR-format mock drafts.
Data as of September 10, 2025.
| # | Name | Pos | Team | ADP | Bye |
|---|---|---|---|---|---|
| 1 | Christian McCaffrey | RB | SF | 1.08 | 14 |
| 2 | George Kittle | TE | SF | 4.08 | 14 |
| 3 | Brock Purdy | QB | SF | 6.09 | 14 |
| 4 | Ricky Pearsall | WR | SF | 7.06 | 14 |
| 5 | Jauan Jennings | WR | SF | 7.09 | 14 |
| 6 | San Francisco Defense | DEF | SF | 12.08 | 14 |
| 7 | Brandon Aiyuk | WR | SF | 12.11 | 14 |
Christian McCaffrey's current ADP is 1.08, which is the 8th pick of the 1st round, and 8th selection overall.
George Kittle's current ADP is 4.08, which is the 8th pick of the 4th round, and 43rd selection overall.
Brock Purdy's current ADP is 6.09, which is the 9th pick of the 6th round, and 69th selection overall.
Ricky Pearsall's current ADP is 7.06, which is the 6th pick of the 7th round, and 78th selection overall.
Jauan Jennings's current ADP is 7.09, which is the 9th pick of the 7th round, and 81st selection overall.
San Francisco Defense's current ADP is 12.08, which is the 8th pick of the 12th round, and 139th selection overall.
Brandon Aiyuk's current ADP is 12.11, which is the 11th pick of the 12th round, and 143rd selection overall.
| Week | Home/Away | Opponent |
|---|---|---|
| 1 | Away | Seattle Seahawks |
| 2 | Away | New Orleans Saints |
| 3 | Home | Arizona Cardinals |
| 4 | Home | Jacksonville Jaguars |
| 5 | Away | Los Angeles Rams |
| 6 | Away | Tampa Bay Buccaneers |
| 7 | Home | Atlanta Falcons |
| 8 | Away | Houston Texans |
| 9 | Away | New York Giants |
| 10 | Home | Los Angeles Rams |
| 11 | Away | Arizona Cardinals |
| 12 | Home | Carolina Panthers |
| 13 | Away | Cleveland Browns |
| 15 | Home | Tennessee Titans |
| 16 | Away | Indianapolis Colts |
| 17 | Home | Chicago Bears |
| 18 | Home | Seattle Seahawks |
San Francisco 49ers running back Isaac Guerendo has emerged as a potential drop candidate as dynasty managers prepare for the offseason roster crunch. Between clearing taxi squad spots, adding players, and navigating rookie drafts, dynasty managers may need to make decisions about which rostered players to cut. Guerendo is a prime candidate after an underwhelming second season with the 49ers in 2025. He appeared in 14 games but played exclusively on special teams, never logging an offensive snap. He was buried on the depth chart behind Christian McCaffrey, Brian Robinson Jr., Jordan James, and even fullback Kyle Juszczyk. It was a surprising, harsh development for the Louisville product after he finished as the overall RB48 in PPR leagues with 572 scrimmage yards and five touchdowns in 2024. Evidently, the 49ers don't see Guerendo in their long-term plans, and it's hard to imagine he'll climb the depth chart in 2026, even with Robinson expected to hit free agency. Managers in most dynasty leagues should feel comfortable dropping the 25-year-old.
February 18, 2026 10:02 AM EST
The Minnesota Vikings could be looking to trade for a quarterback this offseason after former first-rounder J.J. McCarthy struggled with injuries and ineffectiveness in his first full year as the starter. The Athletic's Alec Lewis writes that "there is perhaps no candidate who checks more boxes for what the Vikings are looking for than San Francisco 49ers QB Mac Jones." There are a lot of things that could attract the Vikings' front office and head coach Kevin O'Connell. The 27-year-old is a former first-rounder, comes from a Kyle Shanahan offense, and pushes the ball over the middle of the field. He's still under contract with San Fran for another year, but his guaranteed salary for 2026 is only $1 million. The biggest obstacle to Jones potentially landing in Minnesota is the 49ers driving a "hard bargain" for him after he had a solid season filling in for the injured Brock Purdy. To land Jones, the Vikes might have to make the Niners an offer they can't refuse.
February 17, 2026 9:39 AM EST
The Athletic's Vic Tafur writes that it seems as though the San Francisco 49ers "have big plans" for second-year running back Jordan James. Brian Robinson Jr. had a nice season as the backup to star RB Christian McCaffrey, carrying the ball 92 times for 400 yards and two touchdowns in 17 regular-season games, but the 26-year-old will be a free agent in March. James, 21, was taken in the fifth round out of Oregon last year, but he played in only three games and didn't have a single touch out of the backfield. Isaac Guerendo is an obvious cut candidate, but James probably will only see a significant role in San Fran's backfield in 2026 if Robinson walks in free agency. James was a healthy scratch for the first 14 games of the 2025 season and only played on special teams to close out the year. If Robinson isn't back next season, James will be an obvious handcuff for the oft-injured CMC.
February 17, 2026 9:22 AM EST
San Francisco 49ers wide receiver Ricky Pearsall is trending up ahead of the NFL offseason. Fellow Niners receiver Jauan Jennings is headed for free agency, and given that his relationship with the team is rocky, it seems likely that he'll sign somewhere else. If Jennings does leave, and Brandon Aiyuk also departs as expected, that will open the door for Pearsall to step into the No. 1 receiver role. He showed the ability to handle a top role at times in 2025, but injuries prevented fantasy managers from being able to fully evaluate him. He ultimately finished his second pro season with 36 catches, 528 yards, and zero touchdowns across nine games. Because of his injury history, it might be tough for the 49ers to trust Pearsall as their No. 1 receiver. We wouldn't be surprised to see them go out and grab a top pass-catcher via trade or free agency, leaving Pearsall in the No. 2 role once again. He can absolutely still offer upside in fantasy football, though. The 49ers have a very capable offense, so Pearsall will be able to turn any workload into fantasy points. He ranks as a fringe top-36 fantasy receiver for 2026 and would jump into the top 24 if the 49ers don't bring in any competition for him.
February 15, 2026 4:31 AM EST
Across 15 games in 2025, San Francisco 49ers wide receiver Jauan Jennings recorded 55 receptions for 643 yards and nine touchdowns on 90 targets. With 49ers wideout Brandon Aiyuk (knee) sidelined for the entirety of 2025 by a knee injury, Jennings emerged as the team's WR1. The 28-year-old is now set to hit unrestricted free agency, but 49ers' general manager John Lynch recently expressed public interest in signing Jennings to a new contract. If Jennings does indeed re-sign with San Francisco, he could see an even greater role in the team's passing game in 2026. San Francisco lost star tight end George Kittle (Achilles) to a torn Achilles in the NFC Wild Card Round in early January, which means Kittle could miss a sizable chunk of the 2026 season. Additionally, 49ers WR2 Ricky Pearsall has had major difficulty staying on the field to this point in his NFL career, playing in just 20 games across his first two professional seasons. Jennings may not carry elite fantasy upside, but he's solidified himself as a reliable producer over the last two seasons in San Francisco.
February 13, 2026 7:58 AM EST
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