These are the top fantasy football players of the San Francisco 49ers as ranked by Average Draft Position (ADP) in PPR-format mock drafts.
Data as of September 10, 2025.
| # | Name | Pos | Team | ADP | Bye |
|---|---|---|---|---|---|
| 1 | Christian McCaffrey | RB | SF | 1.08 | 14 |
| 2 | George Kittle | TE | SF | 4.08 | 14 |
| 3 | Brock Purdy | QB | SF | 6.09 | 14 |
| 4 | Ricky Pearsall | WR | SF | 7.06 | 14 |
| 5 | Jauan Jennings | WR | SF | 7.09 | 14 |
| 6 | San Francisco Defense | DEF | SF | 12.08 | 14 |
| 7 | Brandon Aiyuk | WR | SF | 12.11 | 14 |
Christian McCaffrey's current ADP is 1.08, which is the 8th pick of the 1st round, and 8th selection overall.
George Kittle's current ADP is 4.08, which is the 8th pick of the 4th round, and 43rd selection overall.
Brock Purdy's current ADP is 6.09, which is the 9th pick of the 6th round, and 69th selection overall.
Ricky Pearsall's current ADP is 7.06, which is the 6th pick of the 7th round, and 78th selection overall.
Jauan Jennings's current ADP is 7.09, which is the 9th pick of the 7th round, and 81st selection overall.
San Francisco Defense's current ADP is 12.08, which is the 8th pick of the 12th round, and 139th selection overall.
Brandon Aiyuk's current ADP is 12.11, which is the 11th pick of the 12th round, and 143rd selection overall.
| Week | Home/Away | Opponent |
|---|---|---|
| 1 | Away | Seattle Seahawks |
| 2 | Away | New Orleans Saints |
| 3 | Home | Arizona Cardinals |
| 4 | Home | Jacksonville Jaguars |
| 5 | Away | Los Angeles Rams |
| 6 | Away | Tampa Bay Buccaneers |
| 7 | Home | Atlanta Falcons |
| 8 | Away | Houston Texans |
| 9 | Away | New York Giants |
| 10 | Home | Los Angeles Rams |
| 11 | Away | Arizona Cardinals |
| 12 | Home | Carolina Panthers |
| 13 | Away | Cleveland Browns |
| 15 | Home | Tennessee Titans |
| 16 | Away | Indianapolis Colts |
| 17 | Home | Chicago Bears |
| 18 | Home | Seattle Seahawks |
San Francisco 49ers tight end George Kittle (ankle) was listed as a limited participant at practice again on Thursday, according to Cam Inman of the Bay Area News Group. Kittle missed Week 17 with an ankle injury, but he returned in the Week 18 regular-season finale against the Seattle Seahawks to play 95% of the offensive snaps. The entire San Fran offense struggled mightily last Saturday night, though, and Kittle caught five passes for only 29 yards on seven targets. Barring a setback on Friday, Kittle should be fine to play in the Wild-Card round of the playoffs on Sunday at the Philadelphia Eagles, where he should be heavily targeted with receiver Ricky Pearsall (knee, ankle) likely out. Kittle should be in play as one of the most expensive TEs in DFS action this weekend, even though the Eagles allowed the second-fewest half-PPR fantasy points per game to the position during the regular season.
January 8, 2026 5:57 PM EST
San Francisco 49ers wide receiver Ricky Pearsall (knee, ankle) was seen on a side field during Thursday's practice, according to Matt Barrows of The Athletic. Pearsall is going to go down as a non-participant in practice for the second straight day, which doesn't bode well for his availability on Sunday in the Wild-Card playoff game on the road against the Philadelphia Eagles. The 25-year-old missed six games earlier this year due to a PCL sprain in his right knee, and he aggravated the injury in Week 17. The former first-rounder did not play in the Week 18 regular-season finale against the Seattle Seahawks last Saturday and is on the wrong side of questionable to be active for the first round of the playoffs. If Pearsall misses Sunday's game, Jauan Jennings, Demarcus Robinson, and Kendrick Bourne could all see more targets in the passing game in a tough matchup against Philly's defense.
January 8, 2026 5:08 PM EST
Across 15 games in 2025, San Francisco 49ers wide receiver Jauan Jennings recorded 55 receptions for 643 yards and nine touchdowns on 90 targets. The 28-year-old proved the ability to provide stable production, earning at least five targets in 10 out of his final 11 games of the season. Jennings also established himself as a red zone threat, scoring six touchdowns over his final six outings. Particularly with fellow 49ers wideout Ricky Pearsall (knee, ankle) battling injuries, Jennings appears poised to remain in his team's WR1 role for their Wild Card Weekend matchup against the Philadelphia Eagles. While Jennings may not carry explosive production upside, he's a solid bet for somewhere between five to seven targets and should get some looks in the end zone. Fantasy managers in playoff leagues should view Jennings as a solid wide receiver option entering the postseason.
January 8, 2026 4:31 PM EST
Across 14 games this season, San Francisco 49ers wide receiver Demarcus Robinson recorded just 22 receptions for 276 yards and one touchdown on 35 targets. However, the 31-year-old was more consistently productive down the stretch of the season, hauling in nine catches for 113 yards and a touchdown on 10 targets over his final four games played. With fellow 49ers' wideout Ricky Pearsall (knee, ankle) uncertain to be available for the team's Wild Card Weekend matchup against the Philadelphia Eagles, Robinson could play a key role. With Pearsall sidelined in Week 18, Robinson played a season-high 88% of San Francisco's offensive snaps. If Pearsall is unable to play against Philadelphia, Robinson could be a low-end wide receiver option for fantasy managers in playoff leagues.
Demarcus Robinson player page.
January 8, 2026 4:21 PM EST
Across 16 games in 2025, San Francisco 49ers wide receiver Kendrick Bourne recorded 37 receptions for 551 yards and zero touchdowns on 53 targets. The vast majority of Bourne's production came in early October, when he recorded 15 catches for 284 yards on 20 targets across a two-game stretch. The 30-year-old's role in the San Francisco offense faded down the end of the season, as he hauled in just six catches on nine targets over his final seven games played. However, 49ers wideout Ricky Pearsall's (knee, ankle) status for the team's Wild Card Weekend matchup against the Philadelphia Eagles is in doubt as he battles a PCL sprain in his knee. If Pearsall is held out, Bourne could see a larger role in the 49ers' passing game. Pending Pearsall's availability, Bourne could be a low-end option for fantasy managers in playoff leagues.
January 8, 2026 4:12 PM EST