Who Should I Start? Brandon Aiyuk or Darnell Mooney

Tuesday, August 26, 5:06 PM

The San Francisco 49ers officially placed wide receiver Brandon Aiyuk (knee) on the Reserve/Physically Unable to Perform list to begin the 2025 season, which means he will miss at least the first four contests. Head coach Kyle Shanahan has already said that Aiyuk might be targeting a return around Week 6 on the road against the Tampa Bay Buccaneers. The 27-year-old suffered a torn ACL and MCL in Week 7 of last season, which is why he's not ready for the start of 2025. The former first-round wideout had been a major disappointment in fantasy before his season-ending knee injury, too, as he caught just 25 of 47 targets for 374 yards and didn't find the end zone once in seven games. It's understandable for fantasy managers to want to avoid him altogether this year, although he's still worth drafting in leagues with IR spots. With Aiyuk sidelined, Jauan Jennings (calf) and Ricky Pearsall should serve as the top wideouts in San Fran.

Saturday, September 13, 10:47 AM

Atlanta Falcons wide receiver Darnell Mooney (shoulder) was a full participant in practice on Friday after being limited earlier in the week, and heads into Sunday night's matchup with the Vikings without an injury designation. The 27-year-old should slide back into his role as No. 2 receiver behind Drake London (shoulder), who also practiced fully on Friday. Mooney owned a solid 21.3 percent target share last season with the same receiving corps, although much of that was with Kirk Cousins under center. In the two games he played with Michael Penix Jr. at the helm, Mooney's target share dropped to 17.7 percent. Going up against a tough run defense, the Falcons may prefer to attack Minnesota through the air, but with plenty of receiving options at their disposal and Mooney potentially getting eased back into action, the sixth-year pro should be viewed as a high-end WR4/Flex play in Week 2 with some slight upside in PPR formats.