Who Should I Start? Christian McCaffrey or Jonathan Taylor

Sunday, September 14, 8:39 PM

San Francisco 49ers running back Christian McCaffrey rushed for 55 yards on 13 carries during Sunday's Week 2 victory over the New Orleans Saints. He also caught six of seven targets for an additional 53 receiving yards and one receiving touchdown. Although the veteran playmaker didn't quite eclipse the 100-yard mark, he made up for it by scoring his first touchdown of the 2025 campaign. He also served as a very valuable and dependable pass-catching option for quarterback Mac Jones amidst the injury to Brock Purdy (shoulder). McCaffrey has wasted no time making a big impact in fantasy football, scoring at least 22.7 points (PPR) in each of his first two games this year. There's minimal competition for the 29-year-old in San Francisco, keeping him in the mid-range RB1 tier ahead of Week 3 versus the Arizona Cardinals.

Sunday, September 14, 9:09 PM

Indianapolis Colts running back Jonathan Taylor had a monster game in his team's Week 2 win over the Denver Broncos. The 26-year-old logged 25 carries for 165 yards and also caught two passes for 50 yards and a touchdown. Across the first two games of the season, Taylor has now recorded 313 yards from scrimmage and a touchdown on 48 total touches. The Colts' offense has been surprisingly effective so far overall, dropping 33 points on the Miami Dolphins in Week 1 and 29 on Denver in Week 2. Taylor is a must-start fantasy running back with high-end RB1 upside as long as he stays healthy and the Indianapolis offense remains competent.