Who Should I Start? Christian McCaffrey or Miles Sanders

Thursday, February 5, 5:06 PM

San Francisco 49ers running back Christian McCaffrey was named the 2025 Comeback Player of the Year on Thursday night, according to Matt Barrows of The Athletic. McCaffrey was limited to only four games in 2024 due to Achilles and knee issues, but he played in all 17 regular-season games in 2025 and led the 49ers in both rushing (1,202) and receiving yards (924). The four-time Pro Bowler and three-time first-team All-Pro handled a career-high 311 carries and scored 10 rushing touchdowns while also catching 102 passes on 129 targets with an additional seven trips to the end zone as a receiver. The Offensive Player of the Year in 2023 was the RB1 in half-PPR fantasy scoring this year after he slipped to the late first round of many drafts following his injury-plagued 2024 campaign. CMC is entering his age-30 campaign and has a lengthy injury history, but it's simply too hard to ignore his game-changing dual-threat abilities out of the backfield as the engine of San Fran's offense.

Friday, October 10, 5:02 PM

Dallas Cowboys running back Miles Sanders (ankle, knee) has been moved to season-ending injured reserve, according to Patrick Walker of the Dallas Cowboys. Sanders was limited in practice on Wednesday before missing Thursday's practice, but now his season is over as he deals with multiple injuries to his ankle and knee. The 28-year-old served as the primary backup running back to Javonte Williams over the first four games of the season before missing Week 5. Rookie Jaydon Blue was active in his place and should step into a larger role now with Sanders out. Blue shouldn't be in lineups for Week 6, but he is an interesting speculative pickup ahead of Sunday's game against the Panthers.