Who Should I Start? Isaac Guerendo or Jaydon Blue

Tuesday, October 21, 9:16 PM

San Francisco 49ers running back Isaac Guerendo was thrust into action in his rookie season in the NFL in 2024 because Christian McCaffrey missed most of the year due to injuries. Guerendo finished with 84 rushing attempts for 420 yards and four touchdowns in 16 games (three starts) and also chipped in 15 catches on 16 targets as a pass-catcher for 152 yards. Fantasy managers probably viewed him as a pretty valuable handcuff for the injury-prone CMC going into 2025 drafts, but the Niners' acquisition of Brian Robinson Jr. before the season pretty much killed whatever fantasy appeal he had. Through the first seven weeks of his sophomore campaign, the 25-year-old former fourth-rounder has yet to play an offensive snap with CMC and B-Rob both staying healthy. Instead, Guerendo has been limited to a special teams role, returning five kickoffs for a combined 100 yards.

Monday, November 17, 7:15 PM

Dallas Cowboys rookie running back Jaydon Blue and wide receiver Jonathan Mingo are both healthy scratches for the Monday night game against the Las Vegas Raiders. Blue didn't do anything over the bye week to convince the Cowboys that he deserved to be active in Week 11. The 21-year-old drew rave reviews in training camp during the summer, but he has been active in only four games in his first year in the NFL and has 22 rushing attempts for 65 yards while catching one pass for five yards. The Cowboys elevated Malik Davis to the active 53-man roster, and he will operate as the RB2 behind starter Javonte Williams on Monday. Mingo was activated from the Injured Reserve before the Week 8 game, but he has yet to play so far in 2025.