Who Should I Start? Isaac Guerendo or RJ Harvey

Monday, January 6, 10:31 PM

An MRI exam on Monday morning revealed that San Francisco 49ers rookie running back Isaac Guerendo (ankle, knee) suffered an MCL sprain and an ankle sprain in the loss to the division-rival Arizona Cardinals on Sunday in the Week 18 regular-season finale, according to a source. Guerendo will have plenty of time to heal up in the offseason, and the best news is that he didn't suffer any damage to his ACL. Both of the injuries are to his left leg. The 24-year-old fourth-round pick didn't see much of an opportunity in 2024 until late in the season when both Christian McCaffrey (knee) and Jordan Mason (ankle) were ruled out for the year, but when he did get his chances, he was pretty effective out of the Niners' backfield. Guerendo finished with 5.0 yards per carry for 420 yards and four TDs on 84 carries through 16 games. He should serve as valuable insurance for McCaffrey in 2025.

Thursday, May 29, 3:20 PM

Denver Broncos running back RJ Harvey has become one of the hottest fantasy football names among rookies after being selected in the second round of the 2025 NFL Draft. According to team reporter Andrew Mason, the University of Central Florida product had a strong minicamp and "made another statement" at Thursday's OTA practice. Harvey was the fifth running back off the board last month after rushing for 3,789 yards (6.5 YPC) and 43 rushing touchdowns over the last three seasons. He added 61 receptions for 720 yards and four scores in 41 games. In Sean Payton's offense, expectations are high for the versatile and explosive back. He has minimal competition in the Denver backfield, and he should be utilized heavily as a receiver right away. Harvey should have no problem producing an RB2 season as a rookie, and he has an RB1 ceiling.