Who Should I Start? Joe Mixon or Jonathan Taylor

Thursday, November 20, 12:34 PM

Houston Texans running back Joe Mixon (ankle, foot) is not expected to play this season as he deals with a foot injury from the offseason, according to Ian Rapoport of NFL Network. Mixon will likely stay on the Physically Unable to Perform list through the end of the 2025 season, while the Texans move forward with veteran Nick Chubb and rookie Woody Marks in their backfield. Things had been trending this way for a while, as the Texans haven't been giving any real updates on Mixon for pretty much the entire season. Fantasy managers who are still stashing the 29-year-old in redraft leagues should send him to the waiver wire now. Mixon's injury dates all the way back to spring workouts. One would think he'd be ready for the start of the 2026 campaign, but there has been little information about the exact nature of his injury. Marks, a fourth-rounder in April, has slowly started to see more work and should be the backfield leader over Chubb by the end of the year.

Friday, December 12, 10:30 PM

Indianapolis Colts running back Jonathan Taylor has had a stellar season. The 26-year-old leads the league in several rushing categories, including yards (1,356) and touchdowns (16). He also ranks second in attempts (247), two behind James Cook III (249). At this point, Taylor appears to be well on his way to having the best season of his career. Unfortunately, the 2020 No. 41 overall pick has cooled since finding the end zone three times versus the Atlanta Falcons in Berlin back in Week 10, scoring only once in his last three appearances. With four regular-season games left on the schedule, Indianapolis is looking for a much-needed win over Seattle on Sunday in hopes of climbing back to the top of the AFC South. However, the Colts have to figure out a way to win without Daniel Jones (Achilles), who will miss the remainder of the 2025 campaign. That means Indy will turn to the recently un-retired Philip Rivers or Riley Leonard (knee) to take over under center in Week 15. All things considered, both quarterbacks could have a tough time getting anything going against a formidable Seahawks defense, meaning Taylor may get his number called even more than usual. Granted, JT might not have the easiest day either, considering Seattle has allowed just four rushing touchdowns this season. Still, despite the challenging matchup on the horizon, Taylor remains a must-start in all season-long fantasy formats. On the other hand, DFS managers should consider alternative options.