Who Should I Start? Joe Mixon or Omarion Hampton

Monday, December 29, 1:56 PM

Houston Texans running back Joe Mixon (foot, ankle) will not return this season, league sources told Aaron Wilson of KPRC 2 Sports. The expectation all along has been that Mixon would not return at all in 2025, but now it's official. The Texans haven't released many details on the nature of Mixon's foot/ankle injury, but we know that he hasn't played since back in the spring. The 29-year-old remains on the Non-Football Injury list. At this point, it's fair to wonder if he'll be effective at all if he's able to make it back and play in 2026. The Texans will continue to move forward with rookie Woody Marks as their primary ball-carrier, with veteran Nick Chubb and rookie Jawhar Jordan backing him up heading into the Week 18 regular-season finale against the division-rival Indianapolis Colts.

Sunday, January 11, 7:42 PM

Los Angeles Chargers rookie running back Omarion Hampton (ankle) is officially active for Sunday's playoff contest against the New England Patriots. He had been listed as questionable and missed a pair of practices before being upgraded to a limited participant on Friday. Hampton sat out Week 18 with an ankle injury, but his absence was more of a precaution as Los Angeles rested many starters, and the rookie running back was just four weeks removed from a seven-game absence. He took a little while to get back to 100 percent after the injury, but his 81% snap share and 22 touches from Week 17 should indicate that he's back to a starter's workload. We wouldn't be surprised to see him handle another 20-plus touches against the Patriots, whose run defense started to falter down the stretch but still finished with the third-fewest fantasy points allowed to opposing running backs in 2025.