Who Should I Start? Miles Sanders or James Cook

Friday, October 10, 5:02 PM

Dallas Cowboys running back Miles Sanders (ankle, knee) has been moved to season-ending injured reserve, according to Patrick Walker of the Dallas Cowboys. Sanders was limited in practice on Wednesday before missing Thursday's practice, but now his season is over as he deals with multiple injuries to his ankle and knee. The 28-year-old served as the primary backup running back to Javonte Williams over the first four games of the season before missing Week 5. Rookie Jaydon Blue was active in his place and should step into a larger role now with Sanders out. Blue shouldn't be in lineups for Week 6, but he is an interesting speculative pickup ahead of Sunday's game against the Panthers.

Sunday, November 16, 10:34 PM

Buffalo Bills running back James Cook wasn't very efficient on the ground in Sunday's 44-32 win over the visiting Tampa Bay Buccaneers in Week 11, but he still managed to go over 100 scrimmage yards while securing his first receiving touchdown of the year. Cook had 16 rushing attempts for 48 yards on the ground (3.0 yards per carry) while adding three catches on three targets for a season-high 66 yards through the air and his first receiving TD (eighth total in 2025). The 26-year-old had a tough time finding space to run on Sunday against a stout Buccaneers defensive front, but he salvaged his day for fantasy managers by contributing as a pass-catcher, finishing as Buffalo's second leading receiver. Cook's TD came on a 25-yard reception. He's a must-start in all fantasy formats, but Cook might need more contributions as a pass-catcher again in Week 12 in a tough matchup on the ground against the Houston Texans on Thursday Night Football.