Who Should I Start? Damien Harris or James Cook

Monday, March 25, 9:07 PM

Former New England Patriots running back Damien Harris announced his retirement from professional football on Monday at age 27. The Patriots selected Harris in the third round (87th overall) in the 2019 NFL draft out of Alabama, and he had 449 rushing attempts for 2,094 yards and 20 touchdowns in his four years in New England in 38 regular-season games (34 starts) while adding 40 receptions on 51 targets for an additional 281 receiving yards. Harris spent the 2023 campaign with the Buffalo Bills but played in only six games before suffering a season-ending concussion/neck injury that saw him be taken off the field in an ambulance. He'll end his NFL career after just five seasons, recording 2,188 rushing yards and 21 touchdowns on 427 carries with the Pats and Bills.

Friday, February 13, 7:31 AM

Buffalo Bills running back James Cook III solidified himself as one of the NFL's best running backs in 2025, racking up 1,621 rushing yards and 12 touchdowns on 309 carries across 17 games. The 26-year-old also impacted the game as a receiver, hauling in 33 receptions for 291 yards and two scores. Cook III has always been an efficient player, but he was able to reach new production heights in 2025 thanks to an increase in workload. After logging 239 touches across 16 games played in 2024, Cook III recorded 342 touches in 2025 and still averaged a highly efficient 5.6 yards per touch. Cook III signed a four-year extension with Buffalo before the start of the 2025 season, so he's locked in as the team's lead rusher for the foreseeable future. The Bills also promoted former offensive coordinator Joe Brady to head coach, so it seems unlikely that the team would radically shift its offensive approach going forward. Now that he's proven he can handle a significant workload, Cook III profiles as a high-end running back option for fantasy managers in dynasty formats.