Who Should I Start? Alexander Mattison or James Cook

Tuesday, August 12, 9:32 AM

Miami Dolphins running back Alexander Mattison (neck) was officially placed on injured reserve on Monday. Mattison injured his neck during a preseason game against the Chicago Bears on Sunday and later went for surgery. It was announced on Monday that he would miss the remainder of the year, with the team placing him on IR just as a procedural move to clear roster space. Mattison's absence will open up reps for second-year running back Jaylen Wright and rookie Ollie Gordon II behind starter De'Von Achane.

Friday, February 13, 7:31 AM

Buffalo Bills running back James Cook III solidified himself as one of the NFL's best running backs in 2025, racking up 1,621 rushing yards and 12 touchdowns on 309 carries across 17 games. The 26-year-old also impacted the game as a receiver, hauling in 33 receptions for 291 yards and two scores. Cook III has always been an efficient player, but he was able to reach new production heights in 2025 thanks to an increase in workload. After logging 239 touches across 16 games played in 2024, Cook III recorded 342 touches in 2025 and still averaged a highly efficient 5.6 yards per touch. Cook III signed a four-year extension with Buffalo before the start of the 2025 season, so he's locked in as the team's lead rusher for the foreseeable future. The Bills also promoted former offensive coordinator Joe Brady to head coach, so it seems unlikely that the team would radically shift its offensive approach going forward. Now that he's proven he can handle a significant workload, Cook III profiles as a high-end running back option for fantasy managers in dynasty formats.