Should I Start Brandon Aiyuk?

49ers "Hopeful" Brandon Aiyuk Will Play in 2025

Tuesday, December 2, 11:37 AM

San Francisco 49ers general manager John Lynch said he is "not sure" but "hopeful" when asked if it's realistic to expect wide receiver Brandon Aiyuk (knee) to take the field in 2025, per David Lombardi of The San Francisco Standard. Aiyuk tore multiple ligaments in his knee in Week 7 of the 2024 season and has yet to play in a game since. Aiyuk was one of the most efficient wide receivers in the NFL in the last full season he played back in 2023, recording 75 catches for 1,342 yards and seven touchdowns on 105 targets. However, it appears as though he may not be healthy until 2026. Aiyuk also may be locked into a contract stand-off with the team, as the 49ers reportedly voided guarantees in his current contract. Between the injury and the contractual issues, fantasy managers should likely proceed as though Aiyuk will not play a fantasy-relevant role in 2025.

Start Brandon Aiyuk or Rashod Bateman?

Start Brandon Aiyuk or DeMario Douglas?

Start Darius Slayton or Brandon Aiyuk?

Start Brandon Aiyuk or Xavier Legette?

Start Brandon Aiyuk or Tutu Atwell?

Start Brandon Aiyuk or Romeo Doubs?

Start Brandon Aiyuk or Dyami Brown?

Start Brandon Aiyuk or Joshua Palmer?

Start Brandon Aiyuk or Jalen Tolbert?

Start Marquez Valdes-Scantling or Brandon Aiyuk?

Start Brandon Aiyuk or Jack Bech?

Start Brandon Aiyuk or Kyle Williams?

Start Allen Lazard or Brandon Aiyuk?

Start Brandon Aiyuk or Alec Pierce?

Start Brandon Aiyuk or Nick Westbrook-Ikhine?

Start Brandon Aiyuk or Jalen Nailor?

Start Ray-Ray McCloud III or Brandon Aiyuk?

Start Brandon Aiyuk or Emeka Egbuka?

Start Noah Brown or Brandon Aiyuk?

Start Brandon Aiyuk or Marvin Harrison Jr.?