James Cook III

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James Cook III: James Cook III Bounces Back with Dominant Week 2 Performance

Buffalo Bills running back James Cook III put up a huge game in his team's 41-31 Week 2 win over the Detroit Lions, recording 21 carries for 135 yards and a touchdown. It was a nice bounce-back performance for the 26-year-old, who was held to 69 yards from scrimmage on 16 touches by the Houston Texans in Buffalo's season-opener. Cook III's fantasy production is impacted by the presence of Bills quarterback Josh Allen, who had two rushing touchdowns against Detroit and continues to be Buffalo's preferred option in short-yardage situations. Still, Cook III was the only Bills running back to receive a carry in Week 2, even in a game that his team largely controlled for 60 minutes. Buffalo's offense also looks like one of the best units in football so far, which should give Cook III plenty of chances to score touchdowns. Entering the Bills' Week 3 matchup against the Los Angeles Chargers, Cook III remains a clear fantasy RB1.

Sep. 18, 2026 5:48 AM EST

Who Should You Start?

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Who Should You Draft?

Draft James Cook III or Ashton Jeanty?

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Draft James Cook III or Jeremiyah Love?

Draft James Cook III or Trey McBride?

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Draft Christian Watson or James Cook III?