Fantasy Football Week 5 2-QB Flex Rankings

Last updated: October 6, 2025

These fantasy football rankings are refreshed multiple times per day based on projections provided by RotoWire. Use the rankings and projections below to help figure out who to start/sit in your lineup this week.

Season-Long Dynasty Dynasty Rookies

Standard PPR Half-PPR 2-QB Custom

All QB RB WR TE DDEF PK FLFlex

Rank	Name	Team	Pos	Bye	Proj. FP
1.	Brandon Aiyuk	SF	WR	14	18.9
2.	George Pickens	DAL	WR	10	18.2
3.	De'Von Achane	MIA	RB	12	15.3
4.	Jakobi Meyers	LV	WR	8	15.2
5.	Marvin Harrison Jr.	ARI	WR	8	14.9
6.	Derrick Henry	BAL	RB	7	14.8
7.	Ja'Marr Chase	CIN	WR	10	14.6
8.	Jonathan Taylor	IND	RB	11	13.5
9.	Tetairoa McMillan	CAR	WR	14	13.2
10.	Deebo Samuel Sr.	WAS	WR	12	13.1
11.	Saquon Barkley	PHI	RB	9	12.8
12.	Xavier Worthy	KC	WR	10	12.7
13.	Jaxon Smith-Njigba	SEA	WR	8	12.2
14.	Calvin Ridley	TEN	WR	10	12.2
15.	Breece Hall	NYJ	RB	9	12.0
16.	Emeka Egbuka	TB	WR	9	11.8
17.	Puka Nacua	LAR	WR	8	11.7
18.	Omarion Hampton	LAC	RB	12	11.0
19.	Emari Demercado	ARI	RB	8	11.0
20.	Ashton Jeanty	LV	RB	8	10.9
21.	Travis Hunter	JAX	WR	8	10.6
22.	Christian McCaffrey	SF	RB	14	10.3
23.	Jerry Jeudy	CLE	WR	9	10.3
24.	Kyren Williams	LAR	RB	8	10.2
25.	Darius Slayton	NYG	WR	14	10.1
26.	Rashid Shaheed	NO	WR	11	10.0
27.	Jahmyr Gibbs	DET	RB	8	10.0
28.	Davante Adams	LAR	WR	8	9.8
29.	Zay Flowers	BAL	WR	7	9.7
30.	Stefon Diggs	NE	WR	14	9.7
31.	Nico Collins	HOU	WR	6	9.6
32.	Jaylen Waddle	MIA	WR	12	9.5
33.	Justin Jefferson	MIN	WR	6	9.2
34.	James Cook	BUF	RB	7	9.1
35.	Cam Skattebo	NYG	RB	14	9.1
36.	Chase Brown	CIN	RB	10	9.1
37.	Brian Thomas Jr.	JAX	WR	8	8.8
38.	DeVonta Smith	PHI	WR	9	8.8
39.	Chris Godwin	TB	WR	9	8.8
40.	Tee Higgins	CIN	WR	10	8.8
41.	Rachaad White	TB	RB	9	8.7
42.	Nick Westbrook-Ikhine	MIA	WR	12	8.7
43.	Alvin Kamara	NO	RB	11	8.5
44.	Ladd McConkey	LAC	WR	12	8.4
45.	Jordan Mason	MIN	RB	6	8.2
46.	Amon-Ra St. Brown	DET	WR	8	7.9
47.	Kenneth Walker III	SEA	RB	8	7.6
48.	Cooper Kupp	SEA	WR	8	7.5
49.	Travis Etienne Jr.	JAX	RB	8	7.3
50.	Isiah Pacheco	KC	RB	10	7.1